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c-FOS 抗体 (pThr325)

c-Fos 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN684928
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗原表位
    • 27
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    pThr325
    适用
    • 213
    • 161
    • 142
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 201
    • 39
    • 6
    • 1
    克隆类型
    • 204
    • 42
    多克隆
    标记
    • 107
    • 13
    • 11
    • 9
    • 7
    • 6
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    This c-FOS antibody is un-conjugated
    应用范围
    • 202
    • 79
    • 79
    • 76
    • 40
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    • 34
    • 24
    • 14
    • 12
    • 11
    • 6
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    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    特异性
    This phosphorylation site is homologous to Thr325 in Mouse and Rat.
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Sheep,Pig,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Thr325
    亚型
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Tavares, Pathak: "Helicobacter pylori Secreted Protein HP1286 Triggers Apoptosis in Macrophages via TNF-Independent and ERK MAPK-Dependent Pathways." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 58, (2017) (PubMed).

  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    c-Fos (c-Fos 产品)
    别名
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    背景

    Synonyms: p55, AP-1, C-FOS, Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    基因ID
    2353
    UniProt
    P01100
    途径
    S100 Proteins
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