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beta Catenin 抗体 (pSer33, pSer37)

Name: beta Catenin 抗体 (pSer33, pSer37)
SKU: ABIN683893
Availability: OutOfStock

CATNB 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti-Phospho-Beta-Catenin(Ser33/37) Polyclonal Antibody, Unconjugated (ABIN683893) at 1:200 followed by conjugation to the secondary antibody and DAB staining (beta Catenin 抗体 (pSer33, pSer37))

IHC

Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-Phospho-Beta-Catenin(Ser33/37) Polyclonal Antibody, Unconjugated (ABIN683893) at 1:200 followed by conjugation to the secondary antibody and DAB staining (beta Catenin 抗体 (pSer33, pSer37))

IHC

Formalin-fixed and paraffin embedded human colon cancer tissue labeled with Anti-Beta-Catenin (Ser33 + 37) Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (beta Catenin 抗体 (pSer33, pSer37))

IHC (p)

Formalin-fixed and paraffin embedded human laryngeal carcinoma labeled with Rabbit Anti-Beta-Catenin (Ser33 + 37) Polyclonal Antibody at 1:200 followed by conjugation to the secondary antibody and DAB staining (beta Catenin 抗体 (pSer33, pSer37))

IF (p)

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Beta-Catenin (Ser33 + 37) Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (beta Catenin 抗体 (pSer33, pSer37))

IHC (p)

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-Beta-Catenin (Ser33 + 37) Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (beta Catenin 抗体 (pSer33, pSer37))

IHC (p)

7 images

(1 reference)

产品编号 ABIN683893

发货至: 中国

Datasheet as PDF

抗原 See all beta Catenin (CATNB) 抗体

beta Catenin (CATNB) (Catenin, beta (CATNB))
抗原表位
49

27

25

25

23

19

17

17

16

16

16

15

10

8

7

7

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer33, pSer37
适用
343

254

231

27

23

22

18

16

7

5

5

5

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
286

57

4

1

1
兔
Compatible Secondaries
克隆类型
279

70
多克隆
标记
130

22

11

10

9

9

9

9

9

9

9

9

9

9

9

8

7

7

7

7

7

7

4

4

4

4

4

4

1

1

1
This beta Catenin antibody is un-conjugated
应用范围
214

158

119

117

79

64

62

51

34

31

23

9

7

4

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

These phosphorylation sites are homologous to Ser33 + Ser37 in Mouse and Rat.

交叉反应

人, 小鼠, 大鼠

预测反应

Pig,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugatedsynthetic phosphopeptide derived from human Beta-Catenin around the phosphorylation site of Ser33/37

亚型

IgG

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anti-Catenin, beta (CATNB) (AA 661-781) antibody
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anti-Catenin, beta (CATNB) (C-Term) antibody
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anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

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CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C901 unconjugated

anti-Catenin, beta (CATNB) antibody
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anti-Catenin, beta (CATNB) antibody
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anti-Catenin, beta (CATNB) (AA 764-781) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Tang, He, Shi, Kang, Lyu, Zhou, Zhu, Zhang, Tang: "High Concentration of Aspirin Induces Apoptosis in Rat Tendon Stem Cells via Inhibition of the Wnt/β-Catenin Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 50, Issue 6, pp. 2046-2059, (2018) (PubMed).
抗原

beta Catenin (CATNB) (Catenin, beta (CATNB))

别名

beta Catenin (CATNB 产品)

别名

Bfc antibody, Catnb antibody, Mesc antibody, CTNNB antibody, MRD19 antibody, armadillo antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, beta-catenin antibody, ctnnb1 antibody, CHBCAT antibody, catenin (cadherin associated protein), beta 1 antibody, catenin beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 L homeolog antibody, Ctnnb1 antibody, CTNNB1 antibody, ctnnb1 antibody, ctnnb1.L antibody

背景

Synonyms: CTNNB, MRD19, armadillo, Catenin beta-1, Beta-catenin, CTNNB1, OK/SW-cl.35, PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

基因ID

1499

UniProt

P35222

途径

Peptide Hormone Metabolism