TP53BP1 抗体 (pSer25, pSer29)
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- 抗原 See all TP53BP1 抗体
- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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抗原表位
- pSer25, pSer29
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53BP1 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29
- 亚型
- IgG
- Top Product
- Discover our top product TP53BP1 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).
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Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).
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- 抗原
- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
- 别名
- p53BP1 + (TP53BP1 产品)
- 别名
- TP53BP1 antibody, MGC160112 antibody, 53BP1 antibody, Tp53bp1 antibody, m53BP1 antibody, p202 antibody, Trp53bp1 antibody, tumor protein p53 binding protein 1 antibody, tumor suppressor p53-binding protein 1 antibody, tumor protein p53 binding protein 1 (predicted), 5 prime antibody, transformation related protein 53 binding protein 1 antibody, TP53BP1 antibody, tp53bp1 antibody, LOC100550605 antibody, Trp53bp1 antibody, Tp53bp1 antibody
- 背景
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Synonyms: p202, 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1, TP53BP1
Background: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.
- 基因ID
- 7158
- UniProt
- Q12888
- 途径
- DNA Damage Repair
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