ARFIP2 抗体 (pSer260)
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- 抗原 See all ARFIP2 抗体
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
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抗原表位
- pSer260
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARFIP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human arfaptin 2 around the phosphorylation site of Ser260
- 亚型
- IgG
- Top Product
- Discover our top product ARFIP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
- 别名
- arfaptin 2 (ARFIP2 产品)
- 别名
- POR1 antibody, 2310002N04Rik antibody, POR antibody, Por1 antibody, ARFIP2 antibody, im:7136059 antibody, zgc:112066 antibody, ADP ribosylation factor interacting protein 2 antibody, ADP-ribosylation factor interacting protein 2 antibody, ADP-ribosylation factor interacting protein 2b antibody, ARFIP2 antibody, Arfip2 antibody, arfip2b antibody
- 背景
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Synonyms: ADP ribosylation factor interacting protein 2, Arfaptin 2, ARFIP2, Partner of RAC1, POR1, ARFP2_HUMAN.
Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.
- 基因ID
- 23647
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