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IRF3 抗体 (AA 51-150)

Name: IRF3 抗体 (AA 51-150)
SKU: ABIN682588
Availability: OutOfStock

IRF3 适用: 人, 小鼠, 大鼠, 猴, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-IRF3 Polyclonal Antibody, Unconjugated (ABIN682588) at 1:200 followed by conjugation to the secondary antibody and DAB staining (IRF3 抗体 (AA 51-150))

IHC

Formalin-fixed and paraffin embedded human kidney labeled with Anti-IRF3 Polyclonal Antibody, Unconjugated (ABIN682588) at 1:200 followed by conjugation to the secondary antibody and DAB staining (IRF3 抗体 (AA 51-150))

IHC

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-IRF3 Polyclonal Antibody, Unconjugated (ABIN682588) at 1:200 followed by conjugation to the secondary antibody and DAB staining (IRF3 抗体 (AA 51-150))

IHC

3 images

(1 reference)

产品编号 ABIN682588

发货至: 中国

Datasheet as PDF

抗原 See all IRF3 抗体

IRF3 (Interferon Regulatory Factor 3 (IRF3))
抗原表位
15

14

14

14

14

8

7

6

5

5

4

4

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 51-150
适用
144

85

53

30

17

3

2

2

2

1

1

1

1
人, 小鼠, 大鼠, 猴, Cow
宿主
146

17

2
兔
Compatible Secondaries
克隆类型
133

32
多克隆
标记
89

11

8

7

4

4

4

4

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2
This IRF3 antibody is un-conjugated
应用范围
122

68

37

32

28

26

18

11

11

10

5

4

3

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

Cow, 人, 猴, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human IRF3

亚型

IgG

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anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibody
IRF3 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibody
IRF3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C8 unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibody
IRF3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibody
IRF3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibody
IRF3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) antibody
IRF3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4C3 unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1268-1341) antibody
IRF3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibody
IRF3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Interferon Regulatory Factor 3 (IRF3) (pSer385) antibody
IRF3 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Fan, Li, Zhu, Sui, Chen, Deng, Sui, Wang: "NF-κB is involved in the LPS-mediated proliferation and apoptosis of MAC-T epithelial cells as part of the subacute ruminal acidosis response in cows." in: Biotechnology letters, Vol. 38, Issue 11, pp. 1839-1849, (2016) (PubMed).
抗原

IRF3 (Interferon Regulatory Factor 3 (IRF3))

别名

IRF3 (IRF3 产品)

别名

irf3 antibody, IRF3 antibody, C920001K05Rik antibody, IRF-3 antibody, interferon regulatory factor 3 antibody, interferon regulatory factor 7 antibody, irf3 antibody, IRF3 antibody, irf-3 antibody, Irf3 antibody, IRF7 antibody

背景

Synonyms: Interferon regulatory factor 3, IRF-3, IRF3
Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.

基因ID

3661

UniProt

Q14653

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades