MFN2 抗体 (AA 1-120)
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- 抗原 See all MFN2 抗体
- MFN2 (Mitofusin 2 (MFN2))
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抗原表位
- AA 1-120
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适用
- 人, 小鼠, 大鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MFN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 兔, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Mitofusin 2
- 亚型
- IgG
- Top Product
- Discover our top product MFN2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).
: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).
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Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).
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- 抗原
- MFN2 (Mitofusin 2 (MFN2))
- 别名
- Mitofusin 2 (MFN2 产品)
- 别名
- CG3869 antibody, Dmel\\CG3869 antibody, MARF antibody, Marf-1 antibody, Mfn antibody, anon-WO0125274.3 antibody, dMFN antibody, dMfn antibody, dmfn antibody, marf antibody, mfn antibody, mfn2 antibody, MFN2 antibody, hsg antibody, cmt2a antibody, cprp1 antibody, cmt2a2 antibody, CMT2A antibody, CMT2A2 antibody, CPRP1 antibody, HSG antibody, D630023P19Rik antibody, Fzo antibody, mg:cb01g09 antibody, si:dkeyp-104h9.2 antibody, wu:fb79a11 antibody, mitofusin 2 antibody, Mitochondrial assembly regulatory factor antibody, mitofusin-2 antibody, mitofusin 2 L homeolog antibody, MFN2 antibody, Marf antibody, mfn2 antibody, LOC100186475 antibody, Mfn2 antibody, mfn2.L antibody
- 背景
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Synonyms: HSG, MARF, CMT2A, CPRP1, CMT2A2, Mitofusin-2, Transmembrane GTPase MFN2, MFN2, KIAA0214
Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
- 基因ID
- 9927
- UniProt
- O95140
- 途径
- Skeletal Muscle Fiber Development
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