CD161 抗体 (AA 151-225) (Biotin)
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- 抗原 See all CD161 (KLRB1) 抗体
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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抗原表位
- AA 151-225
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD161 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CD161/NK11
- 亚型
- IgG
- Top Product
- Discover our top product KLRB1 Primary Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
- 别名
- CD161 (KLRB1 产品)
- 别名
- NKR-P1 antibody, KLRB1 antibody, 4930431A04Rik antibody, Gm4696 antibody, Klrb1g antibody, Klrb6 antibody, Ly-55 antibody, Ly55 antibody, NKR-P1G antibody, Nkrp-1e antibody, Nkrp1g antibody, CD161 antibody, CLEC5B antibody, NKR antibody, NKR-P1A antibody, NKRP1A antibody, hNKR-P1A antibody, Klrb1d antibody, Klrb1f antibody, Nkr-p1e antibody, killer cell lectin like receptor B1 antibody, killer cell lectin-like receptor subfamily B member 1 antibody, killer cell lectin-like receptor subfamily B, member 1 antibody, KLRB1 antibody, Klrb1 antibody
- 背景
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Synonyms: NKR, CD161, CLEC5B, NKR-P1, NKRP1A, NKR-P1A, hNKR-P1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, Natural killer cell surface protein P1A, KLRB1
Background: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
- 基因ID
- 3820
- UniProt
- Q12918
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