SMO 抗体 (AA 551-650)
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- 抗原 See all SMO 抗体
- SMO (Smoothened Homolog (Drosophila) (SMO))
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抗原表位
- AA 551-650
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMO antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Smoothened
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment." in: Scientific reports, Vol. 7, Issue 1, pp. 13379, (2019) (PubMed).
: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, (2016) (PubMed).
: "
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GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment." in: Scientific reports, Vol. 7, Issue 1, pp. 13379, (2019) (PubMed).
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- 抗原
- SMO (Smoothened Homolog (Drosophila) (SMO))
- 别名
- Smoothened homolog (SMO 产品)
- 别名
- FZD11 antibody, Gx antibody, SMOH antibody, Smoh antibody, E130215L21Rik antibody, bnb antibody, smoothened antibody, XSmo antibody, smoothened, frizzled class receptor antibody, smoothened, frizzled class receptor L homeolog antibody, SMO antibody, Smo antibody, smo.L antibody, smo antibody
- 背景
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Synonyms: Gx, SMOH, FZD11, Smoothened homolog, SMO, Protein Gx
Background: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
- 基因ID
- 6608
- UniProt
- Q99835
- 途径
- Hedgehog Signaling
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