PKD1 抗体 (AA 131-230) (Biotin)
-
- 抗原 See all PKD1 抗体
- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
-
抗原表位
- AA 131-230
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PKD1 antibody is conjugated to Biotin
-
应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Polycystin 1
- 亚型
- IgG
- Top Product
- Discover our top product PKD1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
- 别名
- Polycystin 1 (PKD1 产品)
- 别名
- PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody
- 背景
-
Synonyms: PBP, Pc-1, TRPP1, Polycystin-1, Autosomal dominant polycystic kidney disease 1 protein, PKD1
Background: Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.
- 基因ID
- 5310
- UniProt
- P98161
- 途径
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
-