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PKD1 抗体 (AA 131-230) (Biotin)

PKD1 适用: 人, 小鼠 ELISA, WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN678085
发货至: 中国
  • 抗原 See all PKD1 抗体
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    抗原表位
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-230
    适用
    • 39
    • 25
    • 10
    • 1
    • 1
    人, 小鼠
    宿主
    • 37
    • 1
    • 1
    克隆类型
    • 38
    • 1
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD1 antibody is conjugated to Biotin
    应用范围
    • 25
    • 16
    • 15
    • 13
    • 13
    • 6
    • 6
    • 3
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Polycystin 1
    亚型
    IgG
    Top Product
    Discover our top product PKD1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
    别名
    Polycystin 1 (PKD1 产品)
    别名
    PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody
    背景

    Synonyms: PBP, Pc-1, TRPP1, Polycystin-1, Autosomal dominant polycystic kidney disease 1 protein, PKD1

    Background: Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions.

    基因ID
    5310
    UniProt
    P98161
    途径
    Myometrial Relaxation and Contraction, Maintenance of Protein Location
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