PIK3CA 抗体 (AA 961-1068)
(1 reference)-
- 抗原 See all PIK3CA 抗体
- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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抗原表位
- AA 961-1068
- 适用
- 人, 小鼠, 大鼠, Cow, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3CA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- Cow, 人, 小鼠, 兔, 大鼠
- 预测反应
- Cow,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PI3KCA
- 亚型
- IgG
- Top Product
- Discover our top product PIK3CA Primary Antibody
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anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 401-600) antibody
PIK3CA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) antibodyPIK3CA 适用: 人 WB, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 1019-1050), (C-Term) antibodyPIK3CA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01702 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 504-533) antibodyPIK3CA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (pTyr317) antibodyPIK3CA 适用: 人, 小鼠, Cow WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Internal Region) antibodyVerified PIK3CA 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (N-Term) antibodyPIK3CA 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 1-206), (Catalytic Subunit alpha) antibodyPIK3CA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Catalytic Subunit alpha) antibodyPIK3CA 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 10E5 unconjugated Recombinant Antibody
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 959-1068) antibodyPIK3CA 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 3G3 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells." in: BioMed research international, Vol. 2014, pp. 768181, (2014) (PubMed).
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: "Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells." in: BioMed research international, Vol. 2014, pp. 768181, (2014) (PubMed).
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- 抗原
- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
- 别名
- PI3KCA (PIK3CA 产品)
- 背景
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Synonyms: MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p11-alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase 11 kDa catalytic subunit alpha, PtdIns-3-kinase subunit p11-alpha, p11alpha, Phosphoinositide-3-kinase catalytic alpha polypeptide, Serine/threonine protein kinase PIK3CA, PIK3CA
Background: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors. Involved in the activation of AKT1 upon stimulation by receptor tyrosine kinases ligands such as EGF, insulin, IGF1, VEGFA and PDGF. Involved in signaling via insulin-receptor substrate (IRS) proteins. Essential in endothelial cell migration during vascular development through VEGFA signaling, possibly by regulating RhoA activity. Required for lymphatic vasculature development, possibly by binding to RAS and by activation by EGF and FGF2, but not by PDGF. Regulates invadopodia formation in breast cancer cells through the PDPK1-AKT1 pathway. Participates in cardiomyogenesis in embryonic stem cells through a AKT1 pathway. Participates in vasculogenesis in embryonic stem cells through PDK1 and protein kinase C pathway. Has also serine-protein kinase activity: phosphorylates PIK3R1 (p85alpha regulatory subunit), EIF4EBP1 and HRAS.
- 基因ID
- 5290
- UniProt
- P42336
- 途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
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