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ITGAV/ITGB1 抗体 (Cy3)

ITGAV/ITGB1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN676721
发货至: 中国
  • 抗原 See all ITGAV/ITGB1 products
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    适用
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAV/ITGB1 antibody is conjugated to Cy3
    应用范围
    • 18
    • 16
    • 12
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
    亚型
    IgG
  • 应用备注
    FCM 1:20-100
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    Abstract
    ITGAV/ITGB1 产品
    Sub Type
    Cocktail
    背景

    Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

    Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

    基因ID
    3685, 3688
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