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ITGAV/ITGB1 抗体

ITGAV/ITGB1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN676718
发货至: 中国
  • 抗原 See all ITGAV/ITGB1 products
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    适用
    • 18
    • 18
    • 18
    • 3
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGAV/ITGB1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Hendesi, Barbe, Safadi, Monroy, Popoff: "Integrin mediated adhesion of osteoblasts to connective tissue growth factor (CTGF/CCN2) induces cytoskeleton reorganization and cell differentiation." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115325, (2015) (PubMed).

  • 抗原
    ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))
    别名
    Integrin Alpha V + Beta 1 (ITGAV/ITGB1 产品)
    背景

    Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

    Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

    基因ID
    3685, 3688
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