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GZMB 抗体 (AA 21-130)

GZMB 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN675354
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    抗原表位
    • 18
    • 15
    • 13
    • 10
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-130
    适用
    • 125
    • 47
    • 24
    • 10
    • 4
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 82
    • 45
    • 2
    克隆类型
    • 80
    • 49
    多克隆
    标记
    • 75
    • 12
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    应用范围
    • 70
    • 42
    • 38
    • 35
    • 17
    • 17
    • 16
    • 13
    • 12
    • 9
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific towards Granzyme B and Granzyme H
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GZMB
    亚型
    IgG
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    Granzyme B (GZMB 产品)
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景

    Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    基因ID
    3002
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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