PODXL 抗体 (AA 451-558)
(1 reference)-
- 抗原 See all PODXL 抗体
- PODXL (Podocalyxin-Like (PODXL))
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抗原表位
- AA 451-558
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PODXL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Podocalyxin
- 亚型
- IgG
- Top Product
- Discover our top product PODXL Primary Antibody
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anti-Podocalyxin-Like (PODXL) antibody
PODXL 适用: 人 WB, IHC, ELISA, FACS, IP, IF 宿主: 小鼠 Monoclonal 4D2G7 unconjugated
anti-Podocalyxin-Like (PODXL) (Extracellular Domain) antibodyPODXL 适用: 人, 大鼠, 兔 WB, IHC, FACS, IP, IF, StM 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 32-458) antibodyPODXL 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) antibodyPODXL 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5F5 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 220-431) antibodyPODXL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 171-404) antibodyPODXL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 310-447) antibodyPODXL 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PODXL-2185 unconjugated
anti-Podocalyxin-Like (PODXL) (AA 153-386) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (AA 408-485) antibodyPODXL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podocalyxin-Like (PODXL) (Extracellular Domain) antibodyPODXL 适用: 人, 大鼠, 兔 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 2A4 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Hydrochloride pioglitazone protects diabetic rats against podocyte injury through preserving glomerular podocalyxin expression." in: Arquivos brasileiros de endocrinologia e metabologia, Vol. 58, Issue 6, pp. 630-9, (2014) (PubMed).
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: "Hydrochloride pioglitazone protects diabetic rats against podocyte injury through preserving glomerular podocalyxin expression." in: Arquivos brasileiros de endocrinologia e metabologia, Vol. 58, Issue 6, pp. 630-9, (2014) (PubMed).
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- 抗原
- PODXL (Podocalyxin-Like (PODXL))
- 别名
- Podocalyxin (PODXL 产品)
- 别名
- Gp200 antibody, PC antibody, PCLP antibody, PCLP-1 antibody, PCB antibody, AW121214 antibody, Ly102 antibody, Pclp1 antibody, podocalyxin antibody, MEP21 antibody, PODXL antibody, Gp135 antibody, PCLP1 antibody, cPCLP1 antibody, podxl antibody, fc18d02 antibody, wu:fc18d02 antibody, Pc antibody, Pcb antibody, Podxl antibody, podocalyxin like antibody, pyruvate carboxylase antibody, podocalyxin-like antibody, PODXL antibody, PC antibody, Podxl antibody, podxl antibody, Pcx antibody
- 背景
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Synonyms: PC, PCLP, Gp2, PCLP-1, Podocalyxin, GCTM-2 antigen, Podocalyxin-like protein 1, PODXL, PCLP1
Background: Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
- 基因ID
- 5420
- UniProt
- O00592
- 途径
- Tube Formation
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