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Notch1 抗体 (AA 2101-2300)

Name: Notch1 抗体 (AA 2101-2300)
SKU: ABIN675114
Availability: OutOfStock

NOTCH1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human endometrial cancer labeled with Anti-Notch1/MOTC Polyclonal Antibody, Unconjugated (ABIN675114) followed by conjugation to the secondary antibody and DAB staining (Notch1 抗体 (AA 2101-2300))

IHC

Formalin-fixed and paraffin embedded human endometrial carcinoma labeled with Anti-Notch1/MOTC Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (Notch1 抗体 (AA 2101-2300))

IHC (p)

2 images

(1 reference)

产品编号 ABIN675114

发货至: 中国

Datasheet as PDF

抗原 See all Notch1 (NOTCH1) 抗体

Notch1 (NOTCH1) (Notch 1 (NOTCH1))
抗原表位
16

15

12

11

7

5

5

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2101-2300
适用
120

87

48

10

3

3

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
98

37

6

3

2

1
兔
Compatible Secondaries
克隆类型
94

49

2
多克隆
标记
66

10

9

8

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This Notch1 antibody is un-conjugated
应用范围
94

46

45

31

26

25

18

17

16

9

9

4

3

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Notch1

亚型

IgG

Top Product

Discover our top product NOTCH1 Primary Antibody
anti-Notch 1 (NOTCH1) antibody (PE)
NOTCH1 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal mN1A PE

anti-Notch 1 (NOTCH1) antibody (APC)
NOTCH1 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal mN1A APC

anti-Notch 1 (NOTCH1) (AA 20-216) antibody
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 unconjugated

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (HRP)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 HRP

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (FITC)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 FITC

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Biotin)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Biotin

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (PE)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 PE

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (APC)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 APC

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (PerCP)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 PerCP

anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Atto 488)
NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Atto 488

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Fan, Xu, Zhao: "Prognostic implication of NOTCH1 in early stage oral squamous cell cancer with occult metastases." in: Clinical oral investigations, (2017) (PubMed).
抗原

Notch1 (NOTCH1) (Notch 1 (NOTCH1))

别名

Notch1/MOTC (NOTCH1 产品)

别名

notch1 antibody, NOTCH1 antibody, hn1 antibody, tan1 antibody, notch antibody, xotch antibody, xnotch antibody, notch-1 antibody, xnotch1 antibody, TAN1 antibody, hN1 antibody, 9930111A19Rik antibody, Mis6 antibody, N1 antibody, Tan1 antibody, lin-12 antibody, NOTCH antibody, Xotch antibody, notch1-a antibody, notch 1 antibody, fibropellin-1 antibody, Notch homolog 1, translocation-associated (Drosophila) antibody, Notch homolog 1, translocation-associated antibody, notch 1 S homeolog antibody, notch1 antibody, LOC100631526 antibody, NOTCH1 antibody, Notch1 antibody, notch1.S antibody

背景

Synonyms: hN1, AOS5, TAN1, AOVD1, Neurogenic locus notch homolog protein 1, Notch 1, Translocation-associated notch protein TAN-1, NOTCH1
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).

基因ID

4851

UniProt

P46531

途径

Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development