PCSK2 抗体 (AA 351-400)
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- 抗原 See all PCSK2 抗体
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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抗原表位
- AA 351-400
- 适用
- 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 马, 兔, Cow, 猴, Pig, Bat, 小鸡, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCSK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Human PCSK2
- 预测反应
- Percent identity by BLAST analysis: Human, Mouse, Dog, Bovine, Rabbit, Horse, Guinea pig, Chicken, Xenopus, Zebrafish (100%) Pig (92%).
- 纯化方法
- Immunoaffinity purified
- 免疫原
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Synthetic peptide located between aa351-400 of human PCSK2 (Q5REC2, NP_002585). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Chicken, Platypus, Lizard, Xenopus, Frog, Salmon, Stickleback, Medaka, Zebrafish (100%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product PCSK2 Primary Antibody
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- 应用备注
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Approved: WB (0.2 - 1 μg/mL)
Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled water
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from PBS with 2 % sucrose
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
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Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element." in: The Journal of biological chemistry, Vol. 273, Issue 40, pp. 26087-93, (1998) (PubMed).
: "Transcription of the human beta enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors." in: Molecular and cellular biology, Vol. 15, Issue 11, pp. 5991-6002, (1995) (PubMed).
: "Structural features of the human gene for muscle-specific enolase. Differential splicing in the 5'-untranslated sequence generates two forms of mRNA." in: European journal of biochemistry / FEBS, Vol. 214, Issue 2, pp. 367-74, (1993) (PubMed).
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Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element." in: The Journal of biological chemistry, Vol. 273, Issue 40, pp. 26087-93, (1998) (PubMed).
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- 抗原
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- 别名
- PCSK2 (PCSK2 产品)
- 别名
- NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody
- 背景
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Name/Gene ID: PCSK2
Subfamily: Serine S8
Family: Protease
Synonyms: PCSK2, Proprotein convertase 2, SPC2, NEC 2, NEC-2, Neuroendocrine convertase 2, PC2, KEX2-like endoprotease 2, NEC2, Prohormone convertase 2 - 基因ID
- 5126
- NCBI登录号
- NP_002585
- UniProt
- P16519
- 途径
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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