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CYR61 抗体 (AA 251-379) (Biotin)

CYR61 适用: 人 WB, ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN674501
发货至: 中国
  • 抗原 See all CYR61 抗体
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    抗原表位
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-379
    适用
    • 48
    • 34
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 3
    • 2
    • 1
    克隆类型
    • 48
    • 4
    多克隆
    标记
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYR61 antibody is conjugated to Biotin
    应用范围
    • 31
    • 13
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Cyr61
    亚型
    IgG
    Top Product
    Discover our top product CYR61 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
    别名
    Cyr61 (CYR61 产品)
    别名
    CCN1 antibody, GIG1 antibody, IGFBP10 antibody, ccn1 antibody, gig1 antibody, Xcyr61 antibody, igfbp10 antibody, MGC69281 antibody, MGC69539 antibody, cyr61-l2 antibody, zgc:158158 antibody, CYR61 antibody, AI325051 antibody, Igfbp10 antibody, cysteine rich angiogenic inducer 61 antibody, cysteine-rich, angiogenic inducer, 61 antibody, cysteine-rich, angiogenic inducer, 61 like 2 antibody, cysteine rich protein 61 antibody, cysteine rich angiogenic inducer 61 S homeolog antibody, CYR61 antibody, Cyr61 antibody, cyr61 antibody, cyr61l2 antibody, cyr61.S antibody
    背景

    Synonyms: CCN1, GIG1, IGFBP10, Protein CYR61, CCN family member 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1, CYR61

    Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

    基因ID
    3491
    UniProt
    O00622
    途径
    Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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