CYR61 抗体 (AA 251-379) (Biotin)
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- 抗原 See all CYR61 抗体
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
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抗原表位
- AA 251-379
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYR61 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Cyr61
- 亚型
- IgG
- Top Product
- Discover our top product CYR61 Primary Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- 别名
- Cyr61 (CYR61 产品)
- 别名
- CCN1 antibody, GIG1 antibody, IGFBP10 antibody, ccn1 antibody, gig1 antibody, Xcyr61 antibody, igfbp10 antibody, MGC69281 antibody, MGC69539 antibody, cyr61-l2 antibody, zgc:158158 antibody, CYR61 antibody, AI325051 antibody, Igfbp10 antibody, cysteine rich angiogenic inducer 61 antibody, cysteine-rich, angiogenic inducer, 61 antibody, cysteine-rich, angiogenic inducer, 61 like 2 antibody, cysteine rich protein 61 antibody, cysteine rich angiogenic inducer 61 S homeolog antibody, CYR61 antibody, Cyr61 antibody, cyr61 antibody, cyr61l2 antibody, cyr61.S antibody
- 背景
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Synonyms: CCN1, GIG1, IGFBP10, Protein CYR61, CCN family member 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1, CYR61
Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
- 基因ID
- 3491
- UniProt
- O00622
- 途径
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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