RASSF1 抗体 (AA 145-260)
(2 references)-
- 抗原 See all RASSF1 抗体
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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抗原表位
- AA 145-260
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASSF1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RASSF1
- 亚型
- IgG
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anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Internal Region) antibody
RASSF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 101-340) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) antibodyRASSF1 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (Center) antibodyRASSF1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340) antibodyRASSF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-340), (Isoform A), (N-Term) antibodyRASSF1 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 23-145) antibodyRASSF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 201-250) antibodyRASSF1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 绵羊, 斑马鱼, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (AA 1-270) antibodyRASSF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1) (C-Term) antibodyRASSF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma." in: International journal of oncology, Vol. 48, Issue 1, pp. 55-66, (2015) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
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: "Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma." in: International journal of oncology, Vol. 48, Issue 1, pp. 55-66, (2015) (PubMed).
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- 抗原
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- 别名
- RASSF1 (RASSF1 产品)
- 别名
- RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
- 背景
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Synonyms: 123F2, RDA32, NORE2A, RASSF1A, REH3P21, Ras association domain-containing protein 1, RASSF1
Background: Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation. Isoform A interacts with CDC2, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
- 基因ID
- 11186
- UniProt
- Q9NS23
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