Aggrecan 抗体 (AA 101-220)
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- 抗原 See all Aggrecan (ACAN) 抗体
- Aggrecan (ACAN)
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抗原表位
- AA 101-220
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适用
- 人, 大鼠, 小鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aggrecan antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 兔, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Aggrecan core protein
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral disc." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2017) (PubMed).
: "Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to Fluoride." in: Biological trace element research, (2016) (PubMed).
: "Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1399-1404, (2016) (PubMed).
: "Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes." in: Integrative biology : quantitative biosciences from nano to macro, (2015) (PubMed).
: "Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantation." in: Biomaterials, Vol. 35, Issue 24, pp. 6332-43, (2014) (PubMed).
: "Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo." in: International journal of molecular medicine, Vol. 32, Issue 5, pp. 1063-8, (2014) (PubMed).
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Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral disc." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2017) (PubMed).
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- 抗原
- Aggrecan (ACAN)
- 别名
- Aggrecan core protein 1 (ACAN 产品)
- 背景
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Synonyms: AGC1, SEDK, AGCAN, CSPG1, MSK16, CSPGCP, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, ACAN
Background: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
- 基因ID
- 176
- UniProt
- P16112
- 途径
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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