ROCK2 抗体 (AA 1001-1300)
(5 references)-
- 抗原 See all ROCK2 抗体
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
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抗原表位
- AA 1001-1300
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ROCK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ROCK2
- 亚型
- IgG
- Top Product
- Discover our top product ROCK2 Primary Antibody
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anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 904-1140) antibody
ROCK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1279-1388) antibodyROCK2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) antibodyKO Validated ROCK2 适用: 人 WB, IP, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1109-1388) antibodyROCK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 652-923) antibodyROCK2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1279-1388) antibodyROCK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) antibodyROCK2 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 10E1 unconjugated Recombinant Antibody
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (N-Term) antibodyROCK2 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 1279-1389) antibodyROCK2 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2) (AA 511-560) antibodyROCK2 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 马, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration." in: eLife, Vol. 10, (2021) (PubMed).
: "Design and evaluation of EphrinA1 mutants with cerebral protective effect." in: Scientific reports, Vol. 7, Issue 1, pp. 1881, (2018) (PubMed).
: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).
: "Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells." in: Cellular signalling, Vol. 31, pp. 87-95, (2017) (PubMed).
: "Vascular endothelial growth factor stimulates endothelial differentiation from mesenchymal stem cells via Rho/myocardin-related transcription factor--a signaling pathway." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 7, pp. 1447-56, (2013) (PubMed).
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: "In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration." in: eLife, Vol. 10, (2021) (PubMed).
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- 抗原
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- 别名
- ROCK2 (ROCK2 产品)
- 别名
- rocka-a antibody, xROK antibody, rock2 antibody, rok2 antibody, ROCK2 antibody, B230113H15Rik antibody, ROKalpha antibody, Rho-kinase antibody, Rock-II antibody, Rock2m antibody, mKIAA0619 antibody, ROCK-II antibody, ROK antibody, Rho-associated, coiled-coil containing protein kinase 2 L homeolog antibody, rho-associated, coiled-coil containing protein kinase 2a antibody, Rho associated coiled-coil containing protein kinase 2 antibody, Rho-associated, coiled-coil containing protein kinase 2 antibody, Rho-associated coiled-coil containing protein kinase 2 antibody, rock2.L antibody, rock2a antibody, ROCK2 antibody, Rock2 antibody
- 背景
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Synonyms: ROCK-II, Rho-associated protein kinase 2, Rho kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, Rho-associated, coiled-coil-containing protein kinase II, p164 ROCK-2, ROCK2, KIAA619
Background: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP3, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p9RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
- 基因ID
- 9475
- UniProt
- O75116
- 途径
- Microtubule Dynamics, WNT signaling, Tube Formation
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