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CD3 抗体 (mFluor™450)

GMP Grade CD3 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHT1 mFluor™450
产品编号 ABIN6731073
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
    适用
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    宿主
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    小鼠
    克隆类型
    • 298
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    单克隆
    标记
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    This CD3 antibody is conjugated to mFluor™450
    应用范围
    • 281
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    Flow Cytometry (FACS)
    原理
    CD3 mFluor™ 450 Antibody
    产品特性
    The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.
    纯化方法
    Purified
    纯度
    >95 %
    质量等级
    GMP Grade
    免疫原
    Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
    克隆位点
    UCHT1
    亚型
    IgG1, kappa
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
    基因ID
    916
    NCBI登录号
    NM_000733
    UniProt
    P07766
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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