PD-L1 抗体
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- 抗原 See all PD-L1 抗体
- PD-L1 (CD274 (PD-L1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PD-L1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- Purified
- 克隆位点
- 29E-2A3
- 亚型
- IgG2b, kappa
- Top Product
- Discover our top product PD-L1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Matching Isotype Control: Purified Mouse IgG2b, κ Isotype Control (ABIN7469802)
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.05 % Proclin300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2~8°C. Do not freeze.
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- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- PD-L1 (PD-L1 产品)
- 别名
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- 背景
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- 基因ID
- 29126
- UniProt
- Q9NZQ7
- 途径
- Cancer Immune Checkpoints
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