PD-L1 抗体 (Biotin)
-
- 抗原 See all PD-L1 抗体
- PD-L1 (CD274 (PD-L1))
-
适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This PD-L1 antibody is conjugated to Biotin
-
应用范围
- Flow Cytometry (FACS)
- 克隆位点
- 10F-9G2
- 亚型
- IgG2b, kappa
- Top Product
- Discover our top product PD-L1 Primary Antibody
-
-
- 应用备注
- For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- 说明
-
Matching Isotype Control: Biotin Rat IgG2b, κ Isotype Control (ABIN7469857)
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2~8°C. Do not freeze.
-
- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- CD274/PD-L1 (PD-L1 产品)
- 别名
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- 背景
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
- 基因ID
- 60533
- UniProt
- Q9EP73
- 途径
- Cancer Immune Checkpoints
-