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LDLR 抗体 (AA 781-860)

Name: LDLR 抗体 (AA 781-860)
SKU: ABIN672111
Availability: OutOfStock

LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

Human colon lysates probed with Anti LDL Receptor Polyclonal Antibody, Unconjugated at 1:3000 for 90 min at 37˚C. (LDLR 抗体 (AA 781-860))

Formalin-fixed and paraffin embedded human rectal carcinoma labeled Anti-LDL receptor Polyclonal Antibody, Unconjugated (ABIN672111) at 1:200, followed by conjugation to the secondary antibody and DAB staining (LDLR 抗体 (AA 781-860))

IHC

Formalin-fixed and paraffin embedded human rectal carcinoma labeled Anti-LDL receptor Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (LDLR 抗体 (AA 781-860))

IHC (p)

3 images

(5 references)

产品编号 ABIN672111

发货至: 中国

Datasheet as PDF

抗原 See all LDLR 抗体

LDLR (Low Density Lipoprotein Receptor (LDLR))
抗原表位
15

8

6

5

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 781-860
适用
80

44

31

16

15

5

2

2

2

2

2

1
人, 小鼠, 大鼠, Hamster, 植物
宿主
68

13

5
兔
Compatible Secondaries
克隆类型
67

19
多克隆
标记
44

7

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This LDLR antibody is un-conjugated
应用范围
59

34

25

19

12

8

8

7

6

2

2

2

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

交叉反应

Hamster, 人, 小鼠, 植物, 大鼠

交叉反应（详细）

Hamster

预测反应

Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human LDL-R

亚型

IgG

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anti-Low Density Lipoprotein Receptor (LDLR) (AA 22-150) antibody
LDLR 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1B10H10 unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) antibody
LDLR 适用: 人 ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 2B10 unconjugated Recombinant Antibody

anti-Low Density Lipoprotein Receptor (LDLR) (AA 497-742) antibody
LDLR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 263-509) antibody
LDLR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 105-205) antibody
LDLR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E7 unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 335-588) antibody
LDLR 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 499-511) antibody
LDLR 适用: 人, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 391-419) antibody
LDLR 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Low Density Lipoprotein Receptor (LDLR) (AA 497-742) antibody
LDLR 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

Kou, Han, Wang, Huang, He, Han, Zhou, Ye, Li: "Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters." in: Life sciences, Vol. 151, pp. 50-60, (2016) (PubMed).

Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).

Gow, Muirhead, Hay, Argyle: "Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is Nonspecific." in: Stem cells and development, Vol. 25, Issue 1, pp. 90-100, (2015) (PubMed).

Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: "The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 21, Issue 11, pp. 1373-81, (2014) (PubMed).
抗原

LDLR (Low Density Lipoprotein Receptor (LDLR))

别名

LDL receptor (LDLR 产品)

别名

FH antibody, FHC antibody, LDLCQ2 antibody, Hlb301 antibody, LDLRA antibody, LDLA antibody, LDL receptor-2 antibody, fhc antibody, ldlcq2 antibody, ldlr antibody, ldlr2-a antibody, LDL receptor 1 antibody, ldlr-a antibody, ldlr-b antibody, low density lipoprotein receptor antibody, low density lipoprotein receptor a antibody, low density lipoprotein receptor S homeolog antibody, low density lipoprotein receptor L homeolog antibody, LDLR antibody, Ldlr antibody, ldlra antibody, ldlr.S antibody, ldlr.L antibody

背景

Synonyms: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR
Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

基因ID

3949

UniProt

P01130

途径

Hepatitis C, Lipid Metabolism