SRCIN1 抗体 (AA 189-287)
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- 抗原 See all SRCIN1 抗体
- SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))
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抗原表位
- AA 189-287
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRCIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for SRCIN1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for SRCIN1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human SRCIN1 recombinant protein (Position: E189-E287).
- 亚型
- IgG
- Top Product
- Discover our top product SRCIN1 Primary Antibody
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anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibody
SRCIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibodySRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibodySRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SRC Kinase Signaling Inhibitor 1 (SRCIN1) (Internal Region) antibodySRCIN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- SRCIN1 (SRC Kinase Signaling Inhibitor 1 (SRCIN1))
- 别名
- SRCIN1 (SRCIN1 产品)
- 别名
- P140 antibody, SNIP antibody, mKIAA1684 antibody, p140Cap antibody, Snip antibody, si:ch211-278a6.1 antibody, SRC kinase signaling inhibitor 1 antibody, si:ch211-278a6.1 antibody, SRCIN1 antibody, Srcin1 antibody
- 背景
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Synonyms: SRC kinase signaling inhibitor 1, SNAP-25-interacting protein, SNIP, p130Cas-associated protein, p140Cap, SRCIN1, KIAA1684, P140
Background: Using yeast 2-hybrid analysis, protein pull-down assays, and mutation analysis, it is showed that the first coiled-coil domain of rat Snip interacted with the N-terminal t-SNARE domain of Snap25 (600322). Biochemical studies demonstrated that Snip was tightly associated with rat brain cytoskeleton. Indirect immunofluorescence and confocal microscopy of rat PC12 pheochromocytoma cells revealed colocalization of Snip with Snap25 in the actin cytoskeleton, particularly in filopodia, lamellipodia, and neuritic extensions, including the tips. Overexpression of Snip or its Snap25-interacting domain inhibited calcium-dependent exocytosis from PC12 cells. It is concluded that SNIP is involved in regulation of neurosecretion, perhaps via its interaction with SNAP25 and the cytoskeleton.
- 基因ID
- 80725
- UniProt
- Q9C0H9
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