SCRIB 抗体 (AA 172-409)
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- 抗原 See all SCRIB 抗体
- SCRIB (Scribbled Homolog (SCRIB))
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抗原表位
- AA 172-409
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SCRIB antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 原理
- Rabbit IgG Polyclonal Anti-Human SCRIBBLE Antibody DyLight® 550 Conjugated, Flow Validated.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG Polyclonal Anti-Human SCRIBBLE Antibody DyLight® 550 Conjugated, Flow Validated.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human SCRIBBLE recombinant protein (Position: F172-K409).
- 亚型
- IgG
- Top Product
- Discover our top product SCRIB Primary Antibody
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- 应用备注
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Application details: Flow Cytometry|1-3 μg/1x106 cells
- 说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- At 2-8°C for one year. Protect from light. Do not freeze.
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- 抗原
- SCRIB (Scribbled Homolog (SCRIB))
- 别名
- SCRIB (SCRIB 产品)
- 背景
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Synonyms: Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Background: SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.
- 基因ID
- 23513
- UniProt
- Q14160
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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