COL17A1 抗体
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- 抗原 See all COL17A1 抗体
- COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COL17A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.
- 序列
- KVFSAYSNVT ADLMDFFQTY GAIQ
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence of human Collagen XVII/COL17A1(KVFSAYSNVTADLMDFFQTYGAIQ).
- 亚型
- IgG
- Top Product
- Discover our top product COL17A1 Primary Antibody
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))
- 别名
- COL17A1 (COL17A1 产品)
- 别名
- col17a1 antibody, fk89a06 antibody, si:ch211-223p8.6 antibody, wu:fk89a06 antibody, COL17A1 antibody, BA16H23.2 antibody, BP180 antibody, BPA-2 antibody, BPAG2 antibody, LAD-1 antibody, Bpag antibody, Bpag2 antibody, collagen type XVII alpha 1 chain antibody, collagen, type XVII, alpha 1b antibody, collagen, type XVII, alpha 1 antibody, Col17a1 antibody, col17a1b antibody, COL17A1 antibody
- 背景
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Synonyms: Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120 kDa linear IgA dermatosis antigen, Linear IgA disease antigen 1, LAD-1, 97 kDa linear IgA bullous dermatosis antigen, 97 kDa LAD antigen, 97-LAD, Linear IgA bullous disease antigen of 97 kDa, LABD97, COL17A1, BP180, BPAG2
Background: Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion. It is mapped to 10q25.1. This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
- 基因ID
- 1308
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