FGFR2 抗体 (AA 21-120)
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- 抗原 See all FGFR2 抗体
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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抗原表位
- AA 21-120
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGFR2 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FGFR2
- 亚型
- IgG
- Top Product
- Discover our top product FGFR2 Primary Antibody
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anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-100) antibody
FGFR2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-51), (N-Term) antibodyFGFR2 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01567 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 621-723) antibodyFGFR2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37) antibodyFGFR2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 245-345) antibodyFGFR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) antibodyFGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB17696 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (C-Term) antibodyFGFR2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibodyFGFR2 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB15689 unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 794-821) antibodyFGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibodyFGFR2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- 别名
- FGFR2 (FGFR2 产品)
- 别名
- FGFR2 antibody, FGFR2IIIb antibody, bek antibody, bfr-1 antibody, cd332 antibody, cek3 antibody, cfd1 antibody, ect1 antibody, fgfr-2 antibody, jws antibody, k-sam antibody, kgfr antibody, tk14 antibody, tk25 antibody, xfgfr2 antibody, DKFZp469H1521 antibody, BBDS antibody, BEK antibody, BFR-1 antibody, CD332 antibody, CEK3 antibody, CFD1 antibody, ECT1 antibody, JWS antibody, K-SAM antibody, KGFR antibody, TK14 antibody, TK25 antibody, AU043015 antibody, AW556123 antibody, Bek antibody, Fgfr-2 antibody, Fgfr-7 antibody, Fgfr7 antibody, KGFRTr antibody, svs antibody, FGF-R antibody, fgfr72IIIb antibody, FGFR antibody, fc56c05 antibody, wu:fc56c05 antibody, fibroblast growth factor receptor 2 antibody, fibroblast growth factor receptor 2 L homeolog antibody, FGFR2 antibody, LOC100084641 antibody, fgfr2 antibody, Fgfr2 antibody, fgfr2.L antibody
- 背景
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Synonyms: BEK, JWS, BBDS, CEK3, CFD1, ECT1, KGFR, TK14, TK25, BFR-1, CD332, K-SAM, Fibroblast growth factor receptor 2, FGFR-2, Keratinocyte growth factor receptor, FGFR2, KSAM
Background: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.
- 基因ID
- 2263
- UniProt
- P21802
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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