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MAPK14 抗体 (AA 141-240)

Name: MAPK14 抗体 (AA 141-240)
SKU: ABIN671241
Availability: OutOfStock

MAPK14 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Independently Validated Antibody, image provided by Science Exchange, badge number 029806: L1 HeLa cell lysate, L2 C6/36 cell lysates probed with Anti-P38 MAPK Polyclonal Antibody, Unconjugated at 1:500 overnight at 4˚C. (MAPK14 抗体 (AA 141-240))

MCF-7 cells were stained with p38 MAPK Polyclonal Antibody, Unconjugated at 1:500 in PBS and incubated for two hours at 37°C followed by Goat Anti-Rabbit IgG (H+L) Cy3 conjugated secondary antibody. (MAPK14 抗体 (AA 141-240))

IF (cc)

Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti p38MAPK/MAPK14/p38Alpha Polyclonal Antibody, Unconjugated (ABIN671241) at 1:200 followed by conjugation to the secondary antibody and DAB staining (MAPK14 抗体 (AA 141-240))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti p38MAPK/MAPK14/p38Alpha Polyclonal Antibody, Unconjugated (ABIN671241) at 1:200 followed by conjugation to the secondary antibody and DAB staining (MAPK14 抗体 (AA 141-240))

IHC

4 images

(17 references)

产品编号 ABIN671241

发货至: 中国

Datasheet as PDF

抗原 See all MAPK14 抗体

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
抗原表位
40

33

18

16

15

12

12

10

8

7

6

6

6

6

6

5

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 141-240
适用
251

160

140

28

23

23

16

14

12

12

9

7

6

3

3

3

3

1

1

1

1

1
人, 小鼠, 大鼠, 兔
宿主
221

31

2

1
兔
Compatible Secondaries
克隆类型
214

43
多克隆
标记
132

15

14

11

10

8

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

1

1
This MAPK14 antibody is un-conjugated
应用范围
198

111

75

48

42

42

37

28

27

20

10

9

5

5

4

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Dog

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human P38MAPK

亚型

IgG

Top Product

Discover our top product MAPK14 Primary Antibody
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (pThr180), (pTyr182) antibody
MAPK14 适用: 人, 小鼠, 大鼠, 小鸡, 山羊 WB, ELISA, IHC (p), FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8G4D11 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 19-279) antibody
MAPK14 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (Ser272) antibody
MAPK14 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 260-360) antibody
MAPK14 适用: 人 WB, ELISA, IP, IHC (p), PLA 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 10B11C8 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 295-324), (C-Term) antibody
MAPK14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB2723 unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody
MAPK14 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (C-Term) antibody
MAPK14 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 299-360) antibody
MAPK14 适用: 人, 小鼠 WB, ELISA, IHC, IF/ICC, FACS 宿主: 小鼠 Monoclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Ning, Wang, Gao, Mu, Wang, Liu, Zhu, Meng: "Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro." in: Molecular nutrition & food research, (2017) (PubMed).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, (2017) (PubMed).

Li, Cheng, Nie, Lai, Hu, Luo, Li, Li et al.: "Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt ..." in: Biological trace element research, (2017) (PubMed).

Li, Wang, Zhou, Zhang, Le, He: "Downregulation of BRAF-activated non-coding RNA suppresses the proliferation, migration and invasion, and induces apoptosis of hepatocellular carcinoma cells." in: Oncology letters, Vol. 14, Issue 4, pp. 4751-4757, (2017) (PubMed).

Zhao, Ding, Liu, Yin, Zhang, Ma: "Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5515-5522, (2017) (PubMed).

Shi, Zhan, Zhao, Wang, Ma: "Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice." in: Biological trace element research, Vol. 173, Issue 2, pp. 333-8, (2016) (PubMed).

Zhang, Zang, Dong, Liu, Wang, Yan, Xu, Liu, Pang: "Effect of vasopressin on hippocampal injury in a rodent model of asphyxial cardiopulmonary arrest." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1385-1392, (2016) (PubMed).

Cai, He, Li, Sun, Lam, Qiao, Qiu: "Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2." in: Oncology reports, Vol. 36, Issue 2, pp. 651-8, (2016) (PubMed).

Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, (2016) (PubMed).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, (2016) (PubMed).

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, (2016) (PubMed).

Zhang, Jing, Niu, Zhang, Ge, Miao, Tang: "Peroxiredoxin 1 has an anti-apoptotic role via apoptosis signal-regulating kinase 1 and p38 activation in mouse models with oral precancerous lesions." in: Oncology letters, Vol. 12, Issue 1, pp. 413-420, (2016) (PubMed).

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, (2015) (PubMed).

Li, Dong, Song, Xu, Liu, Song: "Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling." in: Chemico-biological interactions, Vol. 209, pp. 56-67, (2014) (PubMed).

Wang, Zhu, Man, Guo, Hao: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, (2014) (PubMed).

Wang, Sun, Liu, Yu, Li, Zeng, Chen, Jia: "Upregulation of progranulin by Helicobacter pylori in human gastric epithelial cells via p38MAPK and MEK1/2 signaling pathway: role in epithelial cell proliferation and migration." in: FEMS immunology and medical microbiology, Vol. 63, Issue 1, pp. 82-92, (2012) (PubMed).
抗原

MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

别名

P38 MAPK (MAPK14 产品)

别名

CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, Mxi2 antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody, p38 antibody, p38ALPHA antibody, CRK1 antibody, Csbp1 antibody, Csbp2 antibody, Exip antibody, Hog antibody, Prkm14 antibody, Prkm15 antibody, Sapk2A antibody, p38Hog antibody, p38alpha antibody, p38b antibody, zp38b antibody, MAPK14 antibody, 186F5S antibody, BG:DS00797.3 antibody, CG7393 antibody, D-p38 antibody, D-p38 MAPK antibody, D-p38b antibody, Dm p38b antibody, Dmel\\CG7393 antibody, Dmp38b antibody, Dp38 antibody, Dp38b antibody, ESTS:186F5S antibody, Mpk34C antibody, anon-sts23 antibody, dp38b antibody, p38 MAPK antibody, p38 beta antibody, p38B antibody, p38Kb antibody, p38beta antibody, Crk1 antibody, p38-alpha antibody, p38MAPK antibody, p38a antibody, csbp antibody, mapk14a antibody, mxi2 antibody, sapk2 antibody, sapk2a antibody, AP22.98 antibody, AP22_98 antibody, ATMPK14 antibody, mitogen-activated protein kinase 14 antibody, SAPK2a antibody, MAP kinase 14A antibody, MAP kinase p38a antibody, MAPK 14A antibody, fk28c03 antibody, hm:zeh1243 antibody, wu:fk28c03 antibody, zp38a antibody, P38C-CRK antibody, mitogen-activated protein kinase 14 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14b antibody, p38b MAP kinase antibody, mitogen-activated protein kinase 14 S homeolog antibody, mitogen-activated protein kinase 14a antibody, CRK proto-oncogene, adaptor protein antibody, MAPK14 antibody, Mapk14 antibody, mapk14b antibody, p38b antibody, mapk14.S antibody, MPK14 antibody, mapk14a antibody, CRK antibody

背景

Synonyms: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA, Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, MAPK14
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

基因ID

1432

UniProt

Q16539

途径

MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins