BTLA 抗体 (AA 221-289)
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- 抗原 See all BTLA 抗体
- BTLA (B and T Lymphocyte Associated (BTLA))
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抗原表位
- AA 221-289
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BTLA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human B and T-lymphocyte attenuator
- 亚型
- IgG
- Top Product
- Discover our top product BTLA Primary Antibody
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B12A7 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 101-150) antibodyBTLA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 190-289) antibodyBTLA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (C-Term) antibodyBTLA 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BTLA (B and T Lymphocyte Associated (BTLA))
- 别名
- CD272 (BTLA 产品)
- 别名
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- 背景
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Synonyms: BTLA1, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, BTLA
Background: B and T lymphocyte attenuator (BTLA), an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, and attenuates production of interleukin 2 (IL-2). BTLA-deficient T cells show increased proliferation, and BTLA-deficient mice have increased specific antibody responses and enhanced sensitivity to experimental autoimmune encephalomyelitis. B7x, a peripheral homolog of B7, is a ligand of BTLA. Thus, BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).
- 基因ID
- 151888
- UniProt
- Q7Z6A9
- 途径
- Cancer Immune Checkpoints
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