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SMAD7 抗体 (AA 1-100)

Name: SMAD7 抗体 (AA 1-100)
SKU: ABIN670206
Availability: OutOfStock

SMAD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

Mouse lung lysate probed with Anti-Smad7 + Smad6 Polyclonal Antibody at 1:5000 90min in 37˚C. (SMAD7 抗体 (AA 1-100))

Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Smad7/Smad6 Polyclonal Antibody (ABIN670206), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (SMAD7 抗体 (AA 1-100))

IHC

Mouse placenta lysate probed with Anti-Smad7 + Smad6 Polyclonal Antibody at 1:5000 90min in 37˚C. (SMAD7 抗体 (AA 1-100))

Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Smad7/Smad6 Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (SMAD7 抗体 (AA 1-100))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat lung, Antigen retrieval by boiling in sodium citrate buffer (pH6. (SMAD7 抗体 (AA 1-100))

IHC (p)

5 images

(3 references)

产品编号 ABIN670206

发货至: 中国

Datasheet as PDF

抗原 See all SMAD7 抗体

SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
抗原表位
15

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-100
适用
45

27

25

3

3

2

2

1

1
人, 小鼠, 大鼠
宿主
38

7
兔
Compatible Secondaries
克隆类型
39

6
多克隆
标记
22

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SMAD7 antibody is un-conjugated
应用范围
21

15

13

13

7

7

5

3

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Smad7

亚型

IgG
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibody
SMAD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibody
SMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibody
SMAD7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibody
SMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibody
SMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 36-247) antibody
SMAD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibody
SMAD7 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18598 unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (N-Term) antibody
SMAD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibody
SMAD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 24-73) antibody
SMAD7 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Yang, Ding, Xu, Chen, Ding: "MicroRNA-15a inhibition protects against hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 3699-3705, (2017) (PubMed).

Liu, Shi, Yang, Zhao, Du, Zou, Yu: "Synchronous alteration pattern between serine-threonine kinase receptor-associated protein and Smad7 in pilocarpine-induced rats of epilepsy." in: Synapse (New York, N.Y.), Vol. 68, Issue 6, pp. 275-82, (2014) (PubMed).

Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, (2013) (PubMed).
抗原

SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

别名

Smad7 (SMAD7 产品)

别名

CRCS3 antibody, MADH7 antibody, MADH8 antibody, Smad7a antibody, Madh7 antibody, Smad10 antibody, madh7 antibody, xsmad7 antibody, wu:fj60c10 antibody, SMAD family member 7 antibody, SMAD family member 7 L homeolog antibody, SMAD7 antibody, Smad7 antibody, smad7.L antibody, smad7 antibody

背景

Synonyms: CRCS3, MADH7, MADH8, Mothers against decapentaplegic homolog 7, MAD homolog 7, Mothers against DPP homolog 7, Mothers against decapentaplegic homolog 8, MAD homolog 8, Mothers against DPP homolog 8, SMAD family member 7, SMAD 7, Smad7, hSMAD7
Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).

分子量

46kDa

基因ID

4092

UniProt

O15105

途径

Interferon-gamma Pathway, Cell-Cell Junction Organization