RAB7A 抗体
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- 抗原 See all RAB7A 抗体
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Supplier Product No.
- 600-401-i05
- Supplier
- Rockland
- 原理
- RAB7 Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Rab-7 from rat and New World monkey based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-Rab-7 Antibody was purified by peptide affinity chromatography.
- 免疫原
- Rab-7 Antibody was produced from whole rabbit serum prepared by repeated immunizations at the internal amino acids of human Rab-7 protein.
- 亚型
- IgG
- Top Product
- Discover our top product RAB7A Primary Antibody
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- 应用备注
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Immunohistochemistry_Dilution: 10 μg/mL (paraffin)
Western_Blot_Dilution: 0.5-1 μg/mL
- 说明
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Anti-Rab7 antibody has been tested in IF, IHC (p), and WB. Expect a band approximately 23kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
- 别名
- Rab-7 (RAB7A 产品)
- 背景
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Synonyms: RAB7, Ras-related protein Rab-7a
Background: Anti-Rab7 antibody detects human Rab7. Rab7 is a 207 amino acid transport carrier, belonging to the Rab family of RAS-related GTP-binding proteins with 4 GTP/GDP-binding sites and terminates in sequences such as cys-X-cys, cys-cys or a closely related sequence. Rab7 located in specific intracellular compartments is known to be an important regulator of vesicular transport of proteins from early to late endosomes and lysosome biogenesis. Rab7 accelerates thyroid hormone production controlling aggregation and fusion of late lysosomes. It is ubiquitously expressed in most of the tissues and plays an essential role in maintenance of the perinuclear lysosome compartment. Anti-Rab7 antibody is ideal for investigators involved in caner, NFkappaB , and signaling research, kinase and phosphatase protein research.
Gene Name: RAB7A
- 基因ID
- 7879
- NCBI登录号
- NP_004628
- UniProt
- P51149
- 途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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