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PKA 抗体 (AA 17-100)

PKA 适用: 人, 小鼠 WB, IF (p), IF (cc), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN669576
发货至: 中国
  • 抗原 See all PKA 抗体
    PKA (Protein Kinase A (PKA))
    抗原表位
    • 14
    • 1
    • 1
    • 1
    AA 17-100
    适用
    • 19
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKA antibody is un-conjugated
    应用范围
    • 19
    • 12
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from bovine PKA
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

    Zhou, Tanaka, Matsunaga, Iseki, Watanabe, Matsuki, Ikegaya, Koyama: "Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis." in: Scientific reports, Vol. 5, pp. 19679, (2016) (PubMed).

    Yao, Yue, Yun, Sang: "Chronic SO2 inhalation above environmental standard impairs neuronal behavior and represses glutamate receptor gene expression and memory-related kinase activation via neuroinflammation in rats." in: Environmental research, Vol. 137, pp. 85-93, (2015) (PubMed).

    Haolong, Du, Hongchao, Yang, Wei, Hua, Wenliang, Lei, Po: "Enterovirus 71 VP1 activates calmodulin-dependent protein kinase II and results in the rearrangement of vimentin in human astrocyte cells." in: PLoS ONE, Vol. 8, Issue 9, pp. e73900, (2013) (PubMed).

  • 抗原
    PKA (Protein Kinase A (PKA))
    别名
    PKA alpha + beta (PKA 产品)
    别名
    PKCD antibody, Pkaca antibody, Cs-PKA antibody, PKCA1 antibody, PKA antibody, protein kinase, cAMP dependent, catalytic, alpha antibody, protein kinase cAMP-activated catalytic subunit alpha antibody, Prkaca antibody, PRKACA antibody
    背景

    Synonyms: cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB

    Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).

    基因ID
    282323
    UniProt
    P05131
    途径
    SARS-CoV-2 Protein Interactome
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