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ATF3 抗体 (AA 51-150)

ATF3 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN669561
发货至: 中国
  • 抗原 See all ATF3 抗体
    ATF3 (Activating Transcription Factor 3 (ATF3))
    抗原表位
    • 15
    • 14
    • 10
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 69
    • 32
    • 30
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 61
    • 9
    克隆类型
    • 61
    • 9
    多克隆
    标记
    • 35
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATF3 antibody is un-conjugated
    应用范围
    • 55
    • 29
    • 28
    • 15
    • 12
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ATF3
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Smith, Seto, Vivekanandan-Giri, Yuan, Playford, Manna, Hasni, Kuai, Mehta, Schwendeman, Pennathur, Kaplan et al.: "Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription ..." in: Annals of the rheumatic diseases, (2016) (PubMed).

    Aguirre, López-Alonso, González-López, Amado-Rodríguez, Batalla-Solís, Astudillo, Blázquez-Prieto, Fernández, Galván, dos Santos, Albaiceta: "Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 6, pp. 665-76, (2014) (PubMed).

    Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

    Hu, Li, Li: "MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).

    Feng, Sun, Wu, Lu, Qu, Sun, Tian, Zhang, Li, Liu: "Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2064-70, (2013) (PubMed).

  • 抗原
    ATF3 (Activating Transcription Factor 3 (ATF3))
    别名
    ATF3 (ATF3 产品)
    别名
    zgc:55526 antibody, ATF3 antibody, LRG-21 antibody, LRF-1 antibody, LRFI antibody, atf-3 antibody, activating transcription factor 3 antibody, activating transcription factor 3 L homeolog antibody, atf3 antibody, ATF3 antibody, Atf3 antibody, atf3.L antibody
    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3

    Background: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

    基因ID
    467
    UniProt
    P18847
    途径
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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