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ATF3 抗体 (AA 51-150)

ATF3 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN669561
发货至: 中国
  • 抗原 See all ATF3 抗体
    ATF3 (Activating Transcription Factor 3 (ATF3))
    抗原表位
    • 15
    • 12
    • 11
    • 8
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 68
    • 31
    • 29
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 11
    克隆类型
    • 57
    • 12
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATF3 antibody is un-conjugated
    应用范围
    • 52
    • 27
    • 27
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ATF3
    亚型
    IgG
    Top Product
    Discover our top product ATF3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Smith, Seto, Vivekanandan-Giri, Yuan, Playford, Manna, Hasni, Kuai, Mehta, Schwendeman, Pennathur, Kaplan et al.: "Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription ..." in: Annals of the rheumatic diseases, (2016) (PubMed).

    Aguirre, López-Alonso, González-López, Amado-Rodríguez, Batalla-Solís, Astudillo, Blázquez-Prieto, Fernández, Galván, dos Santos, Albaiceta: "Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 6, pp. 665-76, (2014) (PubMed).

    Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

    Hu, Li, Li: "MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).

    Feng, Sun, Wu, Lu, Qu, Sun, Tian, Zhang, Li, Liu: "Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2064-70, (2013) (PubMed).

  • 抗原
    ATF3 (Activating Transcription Factor 3 (ATF3))
    别名
    ATF3 (ATF3 产品)
    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3

    Background: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

    基因ID
    467
    UniProt
    P18847
    途径
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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