MMP1 抗体 (AA 401-464)
(6 references)-
- 抗原 See all MMP1 抗体
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
-
抗原表位
- AA 401-464
-
适用
- 人, 小鼠, 大鼠, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MMP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, Pig, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from rat MMP1
- 亚型
- IgG
- Top Product
- Discover our top product MMP1 Primary Antibody
-
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibody
MMP1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) antibodyMMP1 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6A5 unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 169-464) antibodyMMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 20-280) antibodyMMP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (N-Term) antibodyMMP1 适用: 人, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) antibodyMMP1 适用: 人 WB, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (C-Term) antibodyMMP1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 317-347) antibodyMMP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 401-469) antibodyMMP1 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "Effects of alendronate on lumbar intervertebral disc degeneration with bone loss in ovariectomized rats." in: The spine journal : official journal of the North American Spine Society, (2017) (PubMed).
: "Osteopontin stimulates matrix metalloproteinase expression through the nuclear factor-κB signaling pathway in rat temporomandibular joint and condylar chondrocytes." in: American journal of translational research, Vol. 9, Issue 2, pp. 316-329, (2017) (PubMed).
: "Efficacy of azithromycin and metronidazole combined therapy on rats' gingival overgrowth induced by cyclosporine-A: An experimental animal study." in: Journal of oral biology and craniofacial research, Vol. 6, Issue 3, pp. 219-226, (2016) (PubMed).
: "Impact of three different mouthwashes on the incidence of gingival overgrowth induced by cyclosporine-A: a randomized controlled experimental animal study." in: Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 120, Issue 3, pp. 346-56, (2015) (PubMed).
: "Effect of calcitonin pretreatment on naturally occurring intervertebral disc degeneration in guinea pig." in: International journal of clinical and experimental medicine, Vol. 8, Issue 7, pp. 10367-79, (2015) (PubMed).
: "The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model." in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, (2014) (PubMed).
-
: "Effects of alendronate on lumbar intervertebral disc degeneration with bone loss in ovariectomized rats." in: The spine journal : official journal of the North American Spine Society, (2017) (PubMed).
-
- 抗原
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 别名
- MMP-1 (MMP1 产品)
- 别名
- CLG antibody, CLGN antibody, Mmp1a antibody, CG4859 antibody, Dm1-MMP antibody, Dmel\\CG4859 antibody, MMP-1 antibody, MMP1 antibody, Mmp 1 antibody, dMMP1 antibody, dm1-MMP antibody, dmmp1 antibody, l(2)k04809 antibody, mmp1 antibody, Mmp1 antibody, Mcol-A antibody, Mcola antibody, col4 antibody, mmp18 antibody, Clgn antibody, matrix metallopeptidase 1 antibody, Matrix metalloproteinase 1 antibody, matrix metalloproteinase 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody, matrix metallopeptidase 1a (interstitial collagenase) antibody, matrix metallopeptidase 1 S homeolog antibody, interstitial collagenase antibody, matrix metallopeptidase 8 L homeolog antibody, MMP1 antibody, Mmp1 antibody, RB11133 antibody, Mmp1a antibody, mmp1.S antibody, LOC100727966 antibody, mmp8.L antibody
- 背景
-
Synonyms: CLGN, CLG, 27 kDa interstitial collagenase, collagenase, fibroblast, Fibroblast collagenase, Interstitial collagenase, Matrix metallopeptidase 1 interstitial collagenase, Matrix metalloproteinase-1, Matrix metalloprotease 1, Matrix Metalloproteinase 1, MMP-1, MMP1, MMP1_HUMAN, OTTHUMP00000045866, MMP 1.
Background: The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. In addition, fibronectin like repeats, a hinge region, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, gelatinase, stomelysin and membrane type MMP subfamilies. All MMPs are synthesized as proenzymes, and most of them are secreted from the cells as proenzymes. Thus, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown. MMPs are considered to play an important role in wound healing, apoptosis, bone elongation, embryo development, uterine involution, angiogenesis and tissue remodeling, and in diseases such as multiple sclerosis, Alzheimer's, malignant gliomas, lupus, arthritis, periodontis, glumerulonephritis, atherosclerosis, tissue ulceration, and in cancer cell invasion and metastasis.
- 基因ID
- 300339
- UniProt
- B5DFD5
-
