Factor VIII 抗体 (AA 401-500)
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- 抗原 See all Factor VIII (F8) 抗体
- Factor VIII (F8) (Coagulation Factor VIII (F8))
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抗原表位
- AA 401-500
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适用
- 人, 小鼠, 大鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Factor VIII antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 兔, 大鼠
- 预测反应
- Dog
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from rat factor VIII
- 亚型
- IgG
- Top Product
- Discover our top product F8 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells." in: Molecular vision, Vol. 23, pp. 579-587, (2018) (PubMed).
: "Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1847-1854, (2018) (PubMed).
: "Effects of preserving different veins on flow-through flap survival: An experimental study." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 318-324, (2016) (PubMed).
: "A simple and biosafe method for isolation of human umbilical vein endothelial cells." in: Analytical biochemistry, Vol. 508, pp. 15-8, (2016) (PubMed).
: "Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 6718-26, (2015) (PubMed).
: "Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment." in: Drug design, development and therapy, Vol. 8, pp. 1527-38, (2015) (PubMed).
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Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells." in: Molecular vision, Vol. 23, pp. 579-587, (2018) (PubMed).
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- 抗原
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- 别名
- Factor 8 (F8 产品)
- 别名
- fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody
- 背景
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Synonyms: coagulation factor VIII, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, F8, F8 protein,F8c, FactorVIII, FVIII, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic,
Background: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].
- 分子量
- 267kDa
- 基因ID
- 302470
- UniProt
- Q7TN96
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