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TIMP1 抗体 (AA 103-207)

TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN668331
发货至: 中国
  • 抗原 See all TIMP1 抗体
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    抗原表位
    • 18
    • 16
    • 15
    • 14
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 103-207
    适用
    • 143
    • 77
    • 71
    • 23
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 兔
    宿主
    • 133
    • 54
    • 6
    • 1
    • 1
    克隆类型
    • 136
    • 58
    多克隆
    标记
    • 84
    • 23
    • 16
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    This TIMP1 antibody is un-conjugated
    应用范围
    • 132
    • 65
    • 52
    • 38
    • 25
    • 22
    • 22
    • 20
    • 16
    • 15
    • 11
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 兔, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TIMP-1
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Liang, Xiao, Long, Liu, Li, Liu, Yang: "Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy." in: International journal of molecular medicine, Vol. 40, Issue 6, pp. 1781-1791, (2018) (PubMed).

    Varghese, Joseph, S R, B S, Sreelekha: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." in: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).

    Sassoli, Chellini, Squecco, Tani, Idrizaj, Nosi, Giannelli, Zecchi-Orlandini: "Low intensity 635 nm diode laser irradiation inhibits fibroblast-myofibroblast transition reducing TRPC1 channel expression/activity: New perspectives for tissue fibrosis treatment." in: Lasers in surgery and medicine, Vol. 48, Issue 3, pp. 318-32, (2016) (PubMed).

    Lu, Huang, Shih, Chang, Tsai, Lin, Shih: "Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice." in: PLoS ONE, Vol. 10, Issue 4, pp. e0121077, (2015) (PubMed).

    Ni, Ding, Zhou, Qiu, Tang: "Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats." in: European journal of pharmacology, Vol. 764, pp. 448-456, (2015) (PubMed).

    Watts, Bilska, Diab, Dunster, Bulmer, Barnett, Fraser: "Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury." in: Intensive care medicine experimental, Vol. 3, Issue 1, pp. 31, (2015) (PubMed).

    Sassoli, Nosi, Tani, Chellini, Mazzanti, Quercioli, Zecchi-Orlandini, Formigli: "Defining the role of mesenchymal stromal cells on the regulation of matrix metalloproteinases in skeletal muscle cells." in: Experimental cell research, Vol. 323, Issue 2, pp. 297-313, (2014) (PubMed).

    Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: "The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage." in: Cells, tissues, organs, Vol. 196, Issue 3, pp. 241-50, (2012) (PubMed).

    Jiang, Zhou, Liu: "Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension." in: Die Pharmazie, Vol. 67, Issue 6, pp. 547-52, (2012) (PubMed).

  • 抗原
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    别名
    TIMP-1 (TIMP1 产品)
    别名
    TIMP-1 antibody, TIMP1 antibody, DKFZp468A0912 antibody, CLGI antibody, EPA antibody, EPO antibody, HCI antibody, TIMP antibody, Timp antibody, Clgi antibody, TIMP metallopeptidase inhibitor 1 antibody, tissue inhibitor of metalloproteinase 1 antibody, TIMP1 antibody, Timp1 antibody
    背景

    Synonyms: EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1

    Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP1, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

    基因ID
    7076
    UniProt
    P01033
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