Metabotropic Glutamate Receptor 5 抗体 (C-Term)
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- 抗原 See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Metabotropic Glutamate Receptor 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- mGluR5/1a Antibody
- 交叉反应 （详细）
- Anti-mGluR5/1a antibody is directed against GluR5/1a.
- 纯化方法
- GluR5/1a antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
- 免疫原
- Anti-mGluR5/1a Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
- 亚型
- IgG
- Top Product
- Discover our top product GRM5 Primary Antibody
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anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 458-580) antibody
GRM5 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1A11D10 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 367-380), (Extracellular), (N-Term) antibodyGRM5 适用: 大鼠, 人, 小鼠 WB, IHC, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 419-518) antibodyGRM5 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Alkaline Phosphatase (AP))GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 Alkaline Phosphatase (AP)
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Biotin)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 Biotin
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Biotin)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 Biotin
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- 应用备注
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Immunohistochemistry_Dilution: 1:500
Western_Blot_Dilution: 1:1000
- 说明
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Anti-mGluR5/1a (Rabbit) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 125 kDa monomer and 250 kDa dimer in size corresponding to mGluR5 and mGluR1 proteins in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
- 别名
- Grm5 (GRM5 产品)
- 别名
- GPRC1E antibody, MGLUR5 antibody, mGlu5 antibody, mGluR5 antibody, mGlur5 antibody, 6430542K11Rik antibody, AI850523 antibody, Glu5R antibody, Gprc1e antibody, mGluR5b antibody, glutamate receptor, metabotropic 5 antibody, glutamate metabotropic receptor 5 antibody, GRM5 antibody, Grm5 antibody
- 背景
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Synonyms: mGluR5, Metabotropic Glutamate Receptor 5/1a
Background: mGluR5/1a antibody detects GluR5/1a protein. The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR1 receptor may also be critically involved in limiting the deleterious effects of excitotoxicity. In contrast, the mGluR5 receptor appears to be essential for late phase LTP in area CA1 of the hippocampus. mGluR5/1a is ideal for investigators involved neuronal circuitry and more generally in Neuroscience.
Gene Name: GRM5
- 基因ID
- 24418
- UniProt
- P31424
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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