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CGRP 抗体

Name: CGRP 抗体
SKU: ABIN6658144
Availability: OutOfStock

Rockland 200-301-d15 CALCA 适用: 大鼠 ELISA, WB, IHC, IP, FM, MA 宿主: 小鼠 Monoclonal 4901 unconjugated

Immunocytochemistry of Anti-Calcitonin Gene Related Peptide (CGRP) (Mouse) Antibody - 200-301-D15 Immunocytochemistry of Anti-Calcitonin Gene Related Peptide (CGRP) (Mouse) Antibody. (CGRP 抗体)

ICC

1 image

(3 references)

产品编号 ABIN6658144

Supplier Product No.: 200-301-d15

发货至: 中国

Datasheet as PDF

抗原 See all CGRP (CALCA) 抗体

CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
适用
84

35

10

5

2

1

1

1

1
大鼠
宿主
63

31

14

6

3
小鼠
Compatible Secondaries
克隆类型
72

31
单克隆
标记
67

7

7

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CGRP antibody is un-conjugated
应用范围
68

50

28

13

13

12

11

8

7

6

5

5

3

2

1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM), Multiplex Assay (MA)

Supplier Product No.

200-301-d15

Supplier

Rockland

原理

Calcitonin Gene Related Peptide (CGRP) Antibody

交叉反应（详细）

Anti-CGRP Monoclonal Antibody is directed against rat CGRP protein.

纯化方法

The antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

免疫原

Anti-CGRP Monoclonal Antibody was produced by repeated immunizations with purified rat alpha-CGRP.

克隆位点

4901

亚型

IgG2a

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anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-141) antibody
CALCA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 65-130) antibody
CALCA 适用: 人, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 1-134) antibody
CALCA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) (Internal Region) antibody
CALCA 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 80-141) antibody
CALCA 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) (AA 85-116) antibody
CALCA 适用: 犬 ELISA, WB 宿主: 兔 Polyclonal unconjugated

anti-Calcitonin-Related Polypeptide alpha (CALCA) antibody
CALCA 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4G1H7 unconjugated

应用备注

Immunoprecipitation_Dilution: 1:50-1:100
ELISA_Dilution: 1:5,000
Immunohistochemistry_Dilution: 1:50-1:100
IF_Microscopy_Dilution: User Optimized
Western_Blot_Dilution: not recommended
Other: ICC: 1:50-1:100

说明

Suggested Applications: IF, IHC
Anti-Calcitonin Gene Related Peptide antibody has been tested by ELISA and ICC. This product is not recommended for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Suggested positive controls are dorsal root ganglia, pancreas and gut.

限制

仅限研究用
状态

Liquid

缓冲液

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

有效期

12 months
Morelli, Castaldi, Brown, Streich, Websdale, Taberner, Cerreti, Barenghi, Blum, Sawitzke, Frank, Steffens, Doleschall, Serrao, Ferrarini, Lechner, Prevedel, Heppenstall: "Identification of a population of peripheral sensory neurons that regulates blood pressure." in: Cell reports, Vol. 35, Issue 9, pp. 109191, (2022) (PubMed).

Webber, Clancy, Zhou, Yraola, Homma, García-Añoveros: "Axodendritic versus axosomatic cochlear efferent termination is determined by afferent type in a hierarchical logic of circuit formation." in: Science advances, Vol. 7, Issue 4, (2021) (PubMed).

Dhandapani, Arokiaraj, Taberner, Pacifico, Raja, Nocchi, Portulano, Franciosa, Maffei, Hussain, de Castro Reis, Reymond, Perlas, Garcovich, Barth, Johnsson, Lechner, Heppenstall: "Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons." in: Nature communications, Vol. 9, Issue 1, pp. 1640, (2019) (PubMed).
抗原

CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

别名

Calcitonin Gene Related Peptide (CGRP) (CALCA 产品)

背景

Synonyms: Alpha-type CGRP, Calcitonin gene-related peptide I
Background: CGRP antibody recognizes Calcitonin Gene Related Peptide or CGRP which is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known. CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches. CGRP antibodies have been used successfully in immunoneutralization. Anti-CGRP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: CALCA

基因ID

24241

NCBI登录号

NP_001029128

UniProt

P01256

途径

Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour