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- 抗原 See all CASK 抗体
- CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CASK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼
- 纯化方法
- Anti-CASK Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASK from Mouse, Rat, Human, Zebrafish, and Xenopus based on 100% homology with the immunizing sequence. Cross-reactivity with CASK from other sources has not been determined. Scaffolds research.
- 免疫原
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Immunogen: CASK Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASK/Lin2.
Immunogen Type: Recombinant Protein
- 克隆位点
- S56A-50
- 亚型
- IgG1
- Top Product
- Discover our top product CASK Primary Antibody
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anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 1-300) antibody
CASK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 262-291) antibodyCASK 适用: 人 WB 宿主: 兔 Polyclonal RB15769 unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 470-760) antibodyCASK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) antibodyCASK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (N-Term) antibodyCASK 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 651-750) antibodyCASK 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 564-596), (C-Term) antibodyCASK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1248 unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 589-616) antibodyCASK 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) antibodyCASK 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (AA 1-337), (AA 318-415) antibodyCASK 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-CASK Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~100 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))
- 别名
- CASK (CASK 产品)
- 别名
- CAKI antibody, CAMGUK antibody, CG13412 antibody, CG13413 antibody, CG6703 antibody, CMG antibody, CMG/CASK antibody, Caki antibody, CamGUK antibody, CamguK antibody, Camguk antibody, Cask antibody, Cmg antibody, DLin-2 antibody, Dmel\\CG6703 antibody, RE09582p antibody, caki antibody, camguk antibody, cmg antibody, dCASK antibody, wu:fb70g06 antibody, CAGH39 antibody, FGS4 antibody, LIN2 antibody, MICPCH antibody, MRXSNA antibody, TNRC8 antibody, DXPri1 antibody, DXRib1 antibody, LIN-2 antibody, Pals3 antibody, mLin-2 antibody, CG6703 gene product from transcript CG6703-RF antibody, Peripheral plasma membrane protein CASK antibody, CAMK/CASK protein kinase antibody, peripheral plasma membrane protein CASK antibody, calcium/calmodulin-dependent serine protein kinase b antibody, calcium/calmodulin-dependent serine protein kinase a antibody, calcium/calmodulin dependent serine protein kinase antibody, calcium/calmodulin-dependent serine protein kinase (MAGUK family) antibody, calcium/calmodulin-dependent serine protein kinase (MAGUK family) S homeolog antibody, CASK antibody, Bm1_33725 antibody, LOAG_17286 antibody, Tsp_03763 antibody, caskb antibody, caska antibody, Cask antibody, cask.S antibody
- 背景
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Synonyms: Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase
Background: CASK (calmodulin sensitive kinase) is a ~112 kDa member of the membrane associated quanylate kinase (MAGUK) protein family. It is an adaptor protein with a calcium/calmodulin-dependent protein kinase domain, a SH3 domain, aguanylate kinase homology domain (GUK) and a PDZ domain. CASK links transmembrane proteins to the cytoskeleton and signaling molecules. In particular, CASK binds to Neurexin to stabilize pre- and post-synaptic structrures. While most of CASK proteins are cytoplasmic, a portion of the protein enters the nucleus, where it acts as a transcriptional co-activator. Manifesting the importance of CASK, transgenic mice with insertional mutations die within 24 hours of births. CASK is also localized in the nuclei of basal keratinocytes in newborn rodent skin and developing hair follicles. It may play a role in wound healing.
Gene Name: Cask
- 基因ID
- 29647
- NCBI登录号
- NP_071520
- UniProt
- Q62915
- 途径
- Synaptic Vesicle Exocytosis
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