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GLRA1 抗体 (N-Term)

GLRA1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6658137
发货至: 中国
  • 抗原 See all GLRA1 抗体
    GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 30
    • 16
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 27
    • 4
    • 1
    克隆类型
    • 27
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLRA1 antibody is un-conjugated
    应用范围
    • 20
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Glycine Receptor Antibody
    交叉反应 (详细)
    Anti-Glycine Receptor Antibody is directed against rat Glycine Receptor protein.
    纯化方法
    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
    免疫原
    Anti-Glycine Receptor Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region.
    亚型
    IgG
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    Discover our top product GLRA1 Primary Antibody
  • 应用备注

    Immunohistochemistry_Dilution: 1:1000

    Western_Blot_Dilution: 1:1000

    说明

    Anti-Glycine Receptor (Rabbit) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 48 kDa in size corresponding to the alpha 1 and alpha 2 subunits of the glycine receptor in Western Blots of rat spinal cord and brain stem and in cell extracts.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution_Buffer: Neutral PBS

    Reconstitution_Volume: 50μL

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to restoration.   For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  Dilute only prior to immediate use. 
    有效期
    12 months
  • 抗原
    GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
    别名
    Glra1 (GLRA1 产品)
    别名
    GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody
    背景

    Synonyms: Glycine receptor subunit alpha-1, Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit

    Background: Glycine Receptor Antibody detects Glycine Receptor protein. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission. The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane hyperpolarization. Glycine receptors are anchored at inhibitory chemical synapses by a cytoplasmic protein, gephyrin. The glycine receptor has been used to great advantage in the identification of the binding sites for alcohol on the LGIC family of proteins. These receptors have also been extremely useful in studies of synaptic clustering of receptors. The glycine receptor may also act in concert with an NMDAR subunit to form an excitatory receptor. Therefore, Glycine receptor antibody is ideal for investigators involved in neurological circuitry and more generally in Neuroscience.

    Gene Name: GLRA1

    基因ID
    25674
    NCBI登录号
    NP_037265
    UniProt
    P07727
    途径
    Synaptic Membrane
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