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- 抗原 See all INA 抗体
- INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))
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适用
- 大鼠
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This INA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- Cross reactivity with Alpha Internexin from other species has not been determined.
- 纯化方法
- Anti-Alpha Internexin Antibody is directed against rat Alpha Internexin proteins. The antibody was purified from chicken eggs as an IgY fraction. This antibody is directed against rat alpha internexin protein. Reactivity is expected from mouse and human.
- 免疫原
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Immunogen: Anti-Alpha Internexin Antibody was produced by repeated immunizations with recombinant rat alpha internexin expressed in E. coli.
Immunogen Type: Recombinant Protein
- 亚型
- IgG
- Top Product
- Discover our top product INA Primary Antibody
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anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) (Internal Region) antibody
INA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) (AA 251-350) antibodyINA 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibodyINA 适用: 大鼠 WB, IF 宿主: 小鸡 Polyclonal unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibodyINA 适用: 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) (AA 71-161) antibodyINA 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) (AA 290-319) antibodyINA 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB13854 unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) (AA 290-319) antibodyINA 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 257CT7-1-2 unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibodyINA 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 7T2 unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibodyINA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Internexin Neuronal Intermediate Filament Protein, alpha (INA) antibodyINA 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 小鸡 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-Alpha Internexin antibody is suitable for use in ELISA, Western Blotting and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 66 kDa in size corresponding to the alpha internexin protein in Western blots in the appropriate cell lysate or extract. Minor bands at ~150k are probably covalent dimers and bands at ~50k represent alpha-internexin breakdown products.
ELISA Dilution: 1:50,000
Western Blot Dilution: 1:5000
IF Microscopy Dilution: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.20.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- INA (Internexin Neuronal Intermediate Filament Protein, alpha (INA))
- 别名
- Alpha Internexin (INA 产品)
- 别名
- NEF5 antibody, NF-66 antibody, TXBP-1 antibody, Inexa antibody, Intlaa antibody, Nf66 antibody, AV028420 antibody, NF66 antibody, ina-A antibody, xefiltin antibody, ina-a antibody, inexa antibody, MGC82496 antibody, INA antibody, si:ch211-67n3.6 antibody, nef5 antibody, xina antibody, nf-66 antibody, txbp-1 antibody, MGC69277 antibody, gefiltin antibody, zgc:110516 antibody, internexin neuronal intermediate filament protein alpha antibody, internexin neuronal intermediate filament protein, alpha antibody, internexin neuronal intermediate filament protein alpha S homeolog antibody, low molecular weight neuronal intermediate filament S homeolog antibody, internexin neuronal intermediate filament protein, alpha a antibody, internexin neuronal intermediate filament protein, alpha b antibody, INA antibody, Ina antibody, ina.S antibody, nif.S antibody, inaa antibody, ina antibody, inab antibody
- 背景
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Synonyms: Alpha INX, internexin, NF-66, NEF5
Background: Anti-Alpha Internexin antibody recognizes alpha-internexin which is a Class IV intermediate filament originally discovered as it co-purifies with other neurofilament subunits. Alpha-internexin is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed only in neurons and in large amounts early in neuronal development, but is down-regulated in many neurons as development proceeds. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition, recent studies show a marked up-regulation of alpha-internexin during neuronal regeneration. The use of antibodies to this protein in the study of brain tumors has not been examined to date, but is likely to be of interest. Recently Cairns et al. used this antibody to show that alpha-internexin is an abundant component of the inclusions of neurofilament inclusion body disease (NFID), a serious human neurodegenerative disorder. The antibody was also used to confirm the presence of circulating auto-antibodies to alpha-internexin in the sera of some patients with endocrine autoimmunity, as well as in some normal individuals. Anti-Alpha Internexin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: INA
- 基因ID
- 24503
- UniProt
- P23565
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