SHANK1 抗体 (Internal Region)
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- 抗原 See all SHANK1 抗体
- SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))
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抗原表位
- Internal Region
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SHANK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-SHANK1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with SHANK1 from human, mouse, and rat based on 100% homology with the immunizing sequence. No cross-reactivity against Shank2 or Shank3. Cross-reactivity with Shank1 from other sources has not been determined. Scaffolds research.
- 免疫原
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Immunogen: SHANK1 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an internal region of (SH3/PDZ domains) of rat Shank1.
Immunogen Type: Recombinant Protein
- 克隆位点
- S22-21
- 亚型
- IgG1
- Top Product
- Discover our top product SHANK1 Primary Antibody
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anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody
SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) unconjugated
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (HRP)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (FITC)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (Alkaline Phosphatase (AP))SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) Alkaline Phosphatase (AP)
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (Biotin)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (PE)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) PE
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (APC)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) APC
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (PerCP)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (Atto 488)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1) (AA 469-691) antibody (Atto 594)SHANK1 适用: 大鼠 WB, IHC, AA 宿主: 小鼠 Monoclonal N22-21 (Formerly S22-21) Atto 594
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- 应用备注
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-SHANK1 Antibody is suitable for use in WB and IHC. Expect a band approximately ~190-220 kDa (alternative splice variants) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1-10 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))
- 别名
- SHANK1 (SHANK1 产品)
- 别名
- SPANK-1 antibody, SSTRIP antibody, synamon antibody, Shank1a antibody, Spank1 antibody, Sstrip antibody, SH3 and multiple ankyrin repeat domains 1 antibody, SHANK1 antibody, Shank1 antibody
- 背景
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Synonyms: Spank1, Sstrip, Shank1a, Shank1, SH3 and multiple ankyrin repeat domains protein 1, GKAP/SAPAP-interacting protein, Somatostatin receptor-interacting protein, SSTR-interacting protein, Synamon
Background: Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo.
Gene Name: Spank1
- 基因ID
- 78957
- NCBI登录号
- NP_113939
- UniProt
- Q9WV48
- 途径
- Synaptic Membrane, Maintenance of Protein Location
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