CNTNAP1 抗体
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- 抗原 See all CNTNAP1 抗体
- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CNTNAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- Supplier Product No.
- 200-301-f03
- Supplier
- Rockland
- 原理
- Caspr Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with CASPR from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-CASPR Antibody was purified by Protein G chromatography.
- 过滤
- Sterile filtered
- 免疫原
- CASPR Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASPR.
- 克隆位点
- S65-35
- 亚型
- IgG1
- Top Product
- Discover our top product CNTNAP1 Primary Antibody
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- 应用备注
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Immunoprecipitation_Dilution: User Optimized
Immunohistochemistry_Dilution: 0.1-1.0 μg/mL
IF_Microscopy_Dilution: 1.0-10 μg/mL
Western_Blot_Dilution: 1 μg/mL
- 说明
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Anti-CASPR Antibody is tested by WB, IP, and IHC. Expect a band approximately ~220kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
- 别名
- CASPR (CNTNAP1 产品)
- 背景
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Synonyms: CASPR1, CNTP1, Contactin associated protein 1, NCP1, Paranodin, Neurexin 4, p190, CASPR, NRXN4
Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex. Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Gene Name: CNTNAP1
- 基因ID
- 84008
- NCBI登录号
- NP_114450
- UniProt
- P97846
- 途径
- Cell-Cell Junction Organization
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