CNTNAP1 抗体
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- 抗原 See all CNTNAP1 抗体
- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CNTNAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-CASPR Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CASPR from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with CASPR from other sources has not been determined. Scaffolds research.
- 免疫原
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Immunogen: CASPR Antibody was produced in mice by repeated immunizations with a fusion protein of rat CASPR.
Immunogen Type: Recombinant Protein
- 克隆位点
- S65-35
- 亚型
- IgG1
- Top Product
- Discover our top product CNTNAP1 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-CASPR Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~220 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))
- 别名
- CASPR (CNTNAP1 产品)
- 别名
- CNTNAP1 antibody, CASPR antibody, CNTNAP antibody, NRXN4 antibody, P190 antibody, Caspr antibody, AI841080 antibody, NCP1 antibody, Nrxn4 antibody, p190 antibody, shm antibody, contactin associated protein 1 antibody, contactin associated protein-like 1 antibody, CNTNAP1 antibody, cntnap1 antibody, Cntnap1 antibody
- 背景
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Synonyms: CASPR1, CNTP1, Contactin associated protein 1, NCP1, Paranodin, Neurexin 4, p190, CASPR, NRXN4
Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex. Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.
Gene Name: CNTNAP1
- 基因ID
- 8506
- NCBI登录号
- NP_003623
- UniProt
- P78357
- 途径
- Cell-Cell Junction Organization
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