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GRIA2 抗体 (C-Term)

GRIA2 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S21-32 unconjugated
产品编号 ABIN6658073
发货至: 中国
  • 抗原 See all GRIA2 抗体
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    抗原表位
    • 29
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    C-Term
    适用
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    大鼠
    宿主
    • 92
    • 9
    小鼠
    克隆类型
    • 83
    • 18
    单克隆
    标记
    • 49
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    This GRIA2 antibody is un-conjugated
    应用范围
    • 78
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Anti-GluR2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with GluR2 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with GluR2 from other sources has not been determined. Ion Channels research.
    免疫原

    Immunogen: GluR2 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to a cytoplasmic C-terminus region of rat GluR2.

    Immunogen Type: Recombinant Protein

    克隆位点
    S21-32
    亚型
    IgG1
    Top Product
    Discover our top product GRIA2 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 0.1-1.0 μg/mL

    Application Note: Anti-GluR2 Antibody is suitable for use in WB, IHC, IP, and Immuno-gold EM. Expect a band approximately ~90 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Immunoprecipitation Dilution: User Optimized

    Western Blot Dilution: 1 μg/mL

    IF Microscopy Dilution: 1.0-10 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    别名
    GluR2 (GRIA2 产品)
    别名
    GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
    背景

    Synonyms: Glutamate receptor 2, GluR-2, GLUR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

    Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers. GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium.

    Gene Name: GRIA2

    基因ID
    2891
    NCBI登录号
    NP_000817
    UniProt
    P42262
    途径
    PI3K-Akt Signaling
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