Serotonin Receptor 3A 抗体
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- 抗原 See all Serotonin Receptor 3A (HTR3A) 抗体
- Serotonin Receptor 3A (HTR3A)
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Serotonin Receptor 3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- Supplier Product No.
- 200-401-i12
- Supplier
- Rockland
- 原理
- Serotonin Receptor 3A Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 3A from human, mouse, and rat based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-Serotonin Receptor 3A Antibody was purified by Protein G chromatography.
- 免疫原
- Serotonin Receptor 3A Antibody was produced from whole rabbit serum prepared by repeated immunizations with a mixture of synthetic peptides corresponding to two internal amino acid sequences in rat 5-HT1BR protein.
- 亚型
- IgG
- Top Product
- Discover our top product HTR3A Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 1:500-1:1000
- 说明
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Anti-Serotonin Receptor 3A Antibody is tested for use in IHC and WB. Expect a band approximately 63kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- Serotonin Receptor 3A (HTR3A)
- 别名
- Serotonin Receptor 3A (HTR3A 产品)
- 背景
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Synonyms: 5-HT3
Background: Anti-Serotonin Receptor 3A Antibody detect rat Serotonin Recepto 3A. Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. A 5-HT3 receptor is distinguished from other 5-HT receptors by its structure and function. 5-HT3 receptors span the membrane only four times and are ligand-gated, cation-selective ion channels that mediate neuronal excitation and exocytotic release of neurotransmitters within the peripheral and central nervous systems. Functional studies done on isolated tissues have revealed heterogeneity of this receptor. The human 5-HT3 Receptor Alpha subunits cDNA contains an open reading frame of 1434 base pairs predicting a 23-residue signal peptide and a mature receptor subunit of 455 amino acids. The human subunit exhibits 85 % and 84 % amino acid sequence identity to the mouse and rat receptors, respectively. 5-HT3 Receptor polyclonal antibody shows immunoreactivity in the forebrain (olfactory regions, hippocampal formation and amygdala), sensory and motor nuclei of brainstem and spinal cord. Anti-Serotonin Receptor 3A Antibody is ideal for investigators involved neurobiology research.
Gene Name: Htr3a
- 基因ID
- 79246
- NCBI登录号
- NP_077370
- UniProt
- Q62999
- 途径
- Synaptic Membrane
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