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MBP 抗体

Rockland 200-901-d81 MBP 适用: 大鼠 WB, IF, FM 宿主: 小鸡 Polyclonal unconjugated
Rockland
产品编号 ABIN6658054
Supplier Product No.: 200-901-d81
发货至: 中国
  • 抗原 See all MBP 抗体
    MBP (Myelin Basic Protein (MBP))
    适用
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    大鼠
    宿主
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    小鸡
    克隆类型
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    多克隆
    标记
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    This MBP antibody is un-conjugated
    应用范围
    • 78
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    Western Blotting (WB), Immunofluorescence (IF), Fluorescence Microscopy (FM)
    Supplier Product No.
    200-901-d81
    Supplier
    Rockland
    原理
    Myelin Basic Protein (MBP) Antibody
    交叉反应 (详细)
    Anti-MBP antibody is directed against Myelin basic protein.
    纯化方法
    The antibody is a total IgY fraction.
    免疫原
    Anti-Myelin basic protein Antibody was produced in chicken by repeated immunizations with three peptide sequences conserved in higher vertebrate MBP proteins.
    亚型
    IgG
    Top Product
    Discover our top product MBP Primary Antibody
  • 应用备注

    IF_Microscopy_Dilution: 1:500

    Western_Blot_Dilution: 1:5000

    说明

    Anti-Myelin Basic Protein antibody is tested for use in Western Blotting and IF. Expect a bands of approximately 18 kDa and 22 kDa in size corresponding to MBP proteins in Western blots of rat brain homogenate. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    MBP (Myelin Basic Protein (MBP))
    Abstract
    MBP 产品
    背景

    Synonyms: Myelin A1 protein, Myelin membrane encephalitogenic protein, Myelin basic protein, MBP, Myelin basic protein S, MBP S antibody

    Background: Myelin Basic Protein antibody detects MBP. MBP is one of the major proteins of the myelin sheath surrounding axons in the nervous system. Since it is of relatively low molecular weight and high abundance the protein sequence was determined from purified protein over 30 years ago. The protein is made by oligodendrocytes in the central nervous system, so antibodies to MBP are good markers of this cell type. However, transcripts from the same gene are also expressed in certain hematopoetic lineage cells. In the central nervous system there are there different forms of the protein made by alternate transcription from a single gene, which have molecular weights of 21.5, 18.5, and 17.2 kDa. Since the two lower molecular weight forms are very close in molecular size, MBP antibodies typically show two bands on Western blots, one at about 22 kDa and another at about 18 kDa. Anti-MBP antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.

    Gene Name: MDV1

    基因ID
    24547
    NCBI登录号
    NP_001020465
    UniProt
    P02688
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