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PCDHGA1 抗体 (AA 808-931)

PCDHGA1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal S159-5 unconjugated
产品编号 ABIN6657934
发货至: 中国
  • 抗原 See all PCDHGA1 抗体
    PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 808-931
    适用
    • 16
    • 5
    小鼠
    宿主
    • 14
    • 7
    小鼠
    克隆类型
    • 14
    • 7
    单克隆
    标记
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    This PCDHGA1 antibody is un-conjugated
    应用范围
    • 21
    • 18
    • 17
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    原理
    Protocadherin Gamma (pan) Antibody
    交叉反应 (详细)
    BLAST analysis suggests that it is 99 % identical to human.
    纯化方法
    Anti-Protocadherin Gamma (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
    过滤
    Sterile filtered
    免疫原
    Anti-Protocadherin Gamma (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 808-931 of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins.
    克隆位点
    S159-5
    亚型
    IgG1
    Top Product
    Discover our top product PCDHGA1 Primary Antibody
  • 应用备注

    ELISA_Dilution: 1:10,000

    Western_Blot_Dilution: 1:1000

    Other: ICC/IF: 1:100

    说明

    Anti-Protocadherin Gamma (pan) Antibody is tested for Western Blots and Immunocytochemistry. Expect a band approximately ~100 kDa on specific lysates or tissues. It will cross react with all Gamma-protocadherins -A, -B, and -C. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.1 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
    别名
    Pcdhga1 (PCDHGA1 产品)
    别名
    PCDH-GAMMA-A1 antibody, protocadherin gamma subfamily A, 1 antibody, protocadherin gamma-C5 antibody, PCDHGA1 antibody, LOC478038 antibody, Pcdhga1 antibody
    背景

    Synonyms: PCDH, Protocadherin Gamma antibody, PCDH gamma antibody, PCDH-gamma, PCDHG, Protocadherin gamma , Protocadherin gamma, Gamma Protocadherin (pan), Pan-Gamma-Protocadherin, Pan Gamma Protocadherin

    Background: The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. Anti-Protocadherin Gamma (pan) is ideal for research in Neuroscience, Cell Adhesion and Cell Signaling.

    Gene Name: Protocadherin-Gamma-A1

    基因ID
    93709
    UniProt
    Q91XZ0
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