KDM5B 抗体 (Internal Region)
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- 抗原 See all KDM5B 抗体
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
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抗原表位
- Internal Region
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM5B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 100-401-v92
- Supplier
- Rockland
- 原理
- Jarid1b Antibody
- 交叉反应 (详细)
- Cross reactivity with Jarid1b from other species not tested.
- 纯化方法
- Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
- 过滤
- Sterile filtered
- 免疫原
- Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.
- 亚型
- IgG
- Top Product
- Discover our top product KDM5B Primary Antibody
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- 应用备注
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ELISA_Dilution: 1:100 - 1:200
Western_Blot_Dilution: 1:500
- 说明
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Anti-Jarid1b Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 175 kDa in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))
- 别名
- Jarid1b (KDM5B 产品)
- 背景
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Synonyms: Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1
Background: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.
Gene Name: Kdm5b
- 基因ID
- 10765
- NCBI登录号
- NP_006609
- UniProt
- Q80Y84
- 途径
- Warburg Effect
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