CD207 抗体
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- 抗原 See all CD207 抗体
- CD207 (CD207 Molecule, Langerin (CD207))
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD207 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Supplier Product No.
- 200-401-h89
- Supplier
- Rockland
- 原理
- Langerin Antibody
- 交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with Anti-Langerin from mouse based on 100 % homology with the immunizing sequence.
- 纯化方法
- Anti-Langerin Antibody was purified by Protein G chromatography.
- 免疫原
- Langerin Antibody was produced from whole rabbit serum prepared by repeated immunizations with mouse Langerin protein at an internal amino acid sequence.
- 亚型
- IgG
- Top Product
- Discover our top product CD207 Primary Antibody
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- 应用备注
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Immunohistochemistry_Dilution: 5 μg/mL (paraffin)
Western_Blot_Dilution: 1-3 μg/mL
- 说明
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Anti-Langerin Antibody is tested for use in WB, Flow, Flow-IC, IHC, IHC-Fr, and IHC-P. Expect a band approximately 36kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- CD207 (CD207 Molecule, Langerin (CD207))
- 别名
- Langerin (CD207 产品)
- 背景
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Synonyms: Clec4k, C-type lectin domain family 4 member K, Langerin, CD207
Background: Anti-Langerin Antibody detects mouse Langerin. Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin (CD207) recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin (CD207) is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin (CD207) is thus a potent inducer of membrane superimposition and zippering leading to BG formation. Anti-Langerin Antibody is ideal for investigators involved in Toll Like Receptors, signaling, and extracelluar matrix research.
Gene Name: Cd207
- 基因ID
- 246278
- NCBI登录号
- NP_659192
- UniProt
- Q8VBX4
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